Results 161 to 170 of about 359,802 (303)

Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome

open access: yesEpilepsia, EarlyView.
Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan   +14 more
wiley   +1 more source

Clinical outcomes and learning curve of MRgLITT system for drug‐resistant epilepsy in China: A single‐center retrospective study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) is a minimally invasive technique that allows for real‐time magnetic resonance imaging (MRI) monitoring and precise ablation of epileptogenic lesions. This study reports our initial clinical experience with a domestically developed MRgLITT system in patients with ...
Sichang Chen   +6 more
wiley   +1 more source

Smart Solar Power Site Selection Through a Hybrid Computational Framework of Neuro‐Fuzzy With Genetic Algorithm Optimization

open access: yesEnergy Science &Engineering, EarlyView.
Solar Power plants at various locations a: Pavagada SPP, Karnataka b: Bhadla SPP, Rajasthan c: West Bengal Solar Park ABSTRACT This paper presents a new neuro‐fuzzy multi‐criteria decision‐making (MCDM) framework designed to optimize the selection of solar power plant (SPP) sites across India.
Rajkumari Malemnganbi Devi   +8 more
wiley   +1 more source

When Rare Is Not Small: Amyotrophic Lateral Sclerosis Initiatives and Therapy

open access: yesExploration, EarlyView.
In the precision‐medicine era, rare diseases must not be sidelined in translational infrastructure. The Mr. Cai Lei—led “Ice‐Breaking Team” turns an amyotrophic lateral sclerosis patient community into a sustainable ecosystem, realigning philanthropy, data, and research and development to reshape rare‐disease pipelines and guide precision therapies ...
Yang Liu   +6 more
wiley   +1 more source

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