Results 51 to 60 of about 2,561,539 (256)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Chinese Philosophy, “Postcomparative” Approaches and Transcultural Studies
Asian Studies, 2020 In the previous issue of Asian Studies (May 2020), Vytis Silius published a paper entitled Diversifying Academic Philosophy: The Post-Comparative Turn and Transculturalism, in which he dealt with some basic, significant and hitherto still unsolved ...
Jana S. Rošker
doaj +1 more source
Zhang Yimou's 'Blood simple':cannibalism, remaking and translation in world cinema [PDF]
, 2014 Zhang Yimou’s A Woman, A Gun and A Noodle Shop (2009) remakes the Coen brothers’ Blood Simple (1984) in a way that re-imagines the earlier film in a Chinese setting, adapting and recreating the narrative, but the film cannot be regarded as being aimed ...
Evans, Jonathan
core +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Informality and the Development and Demolition of Urban Villages in the Chinese Peri-urban Area [PDF]
, 2013 The fate of Chinese urban villages (chengzhongcun) has recently attracted both research and policy attention. Two important unaddressed questions are: what are the sources of informality in otherwise orderly Chinese cities; and, will village ...
Webster, C, Wu, F, Zhang, F
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The interaction between nitrogen and phosphorous is a strong predictor of intra-plant variation in nitrogen isotope composition in a desert species [PDF]
Biogeosciences, 2017 Understanding intra-plant variations in δ15N is essential for fully utilizing the potential of δ15N as an integrator of the terrestrial nitrogen (N) cycle and as an indicator of the relative limitation of N and phosphorous (P) on plant growth.
J. Zhang +8 more
doaj +1 more source
Tropical component of the moss Flora of China [PDF]
, 1990 In many ways, it is presumptuous for me to speak on the mosses of the tropical regions of China. Many consider the knowledge about the taxonomy, ecology, and geography of tropical bryophytes inadequate (Pócs 1982; Schuster 1983; Richards 1984), and this ...
Redfearn, Paul L.
core
Culture and the therapeutic relationship: Perspectives from Chinese clients [PDF]
, 2007 Chinese people in the United Kingdom and United States underuse mental health services and, when they do seek help, may find that therapy does not meet their needs. In response to calls in the literature for naturalistic studies of therapy with people of
Jim, J, Pistrang, N
core +1 more source