Results 51 to 60 of about 14,636,985 (313)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Cinematic Representation of Chinese-Indonesians’ Trauma in Jason Iskandar The Day The Sky Roared
This research analyzed a contemporary independent Indonesian film entitled The Day the Sky Roared (2015) that was directed by Jason Iskandar. This 10-minute silent film talked about the anxiety of Chinese-Indonesians through the eyes of a mother and her ...
Anton Sutandio
doaj +1 more source
Changes in Land Use and Ecosystem Service Values of Dunhuang Oasis from 1990 to 2030
Maintaining the integrity and stability of oasis ecosystems is an important topic in the field of ecological research. Assessment of ecosystem services and their changes can provide important support for the sustainable development of oases.
Fan Yi +6 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
In order to analyze the relationship between deep layer moisture infiltration and rainfall in mobile dunes,using YWB-01 deep layer moisture infiltration recorder and soil water dynamics theory,this study explains the rainfall infiltration moisture ...
LI Wei +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Modern Chinese Comics, between center and periphery. Until the XIX century, China considered itself as the center of the world, the “Middle Kingdom”(Zhongguo 中国).
Martina Caschera
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Background: Based on the theory of traditional Chinese medicine (TCM) and pre-epidemiological investigation, Professor Qi Wang classified the entire human population into nine constitutions and put forward the theory of “Nine-Constitution Medicine ...
Shuxian Sun +9 more
doaj +1 more source

