Results 91 to 100 of about 1,997,289 (379)

MEME-ChIP: motif analysis of large DNA datasets

open access: yesBioinform., 2011
Motivation: Advances in high-throughput sequencing have resulted in rapid growth in large, high-quality datasets including those arising from transcription factor (TF) ChIP-seq experiments.
P. Machanick, T. Bailey
semanticscholar   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

以實證觀點檢視我國積體電路電路布局保護法十二年的運作 Empirical Study on the Twelve-Year Practice of Taiwan Integrated Circuits Layout Protection Law [PDF]

open access: yesKējì Fǎxué Pínglùn, 2009
半導體產業是推動我國經濟發展的核心產業之一,而我國積體電路電路布局保護法,號稱是為半導體產業特別的立法,其於1995 年8 月11 日公布施行後,動向也倍受矚目。但是對於此一立法,有人以為係順應產業發展所必要之立法,有人則以為係在美國三○一條款的壓力下不得已的立法,無論如何,本法已施行逾十二年。本文擬以實證研究的方式,檢視積體電路電路布局保護法,在行政執法與司法判決言兩方面十二多年來的實際成效,並探討本法有無達到立法目的,進而分析可能原因,並試著提出法律政策的建議。 Semiconductor ...
張添榜 Tien-Pang Chang
doaj  

« On … on peut se reposer maintenant ? » :Foucault et les multiples subjectivités discursives de Spike [PDF]

open access: yesSlayage, 2023
This article explores Spike’s development via a Foucauldian perspective of power and discourse. Discursive power resides in networks of relationships which allow “subjects [to] freely call upon differing discourses … and therefore, play games of identity”
Herrmann, Andrew F.   +1 more
doaj  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Cyclin-Dependent Kinase 18 Controls Trafficking of Aquaporin-2 and Its Abundance through Ubiquitin Ligase STUB1, Which Functions as an AKAP

open access: yesCells, 2020
Arginine-vasopressin (AVP) facilitates water reabsorption in renal collecting duct principal cells through regulation of the water channel aquaporin-2 (AQP2).
Alessandro Dema   +16 more
doaj   +1 more source

Multichip packaging with thermal insulation [PDF]

open access: yes, 1968
Thermal insulation technique permits low and high power electronic chips to operate in the same package without thermal cross-coupling. An alumina glass shield thermally isolates the low power chip from the high power chip while Kovar substrate acts as a
Mc Inturff, R. G., Mend, W. G.
core   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

SM9‑based CP‑ABE Access Control Scheme under Power IoT

open access: yesTaiyuan Ligong Daxue xuebao
[Purposes] This work has been carried out to achieve fine-grained access control based on the existing power IoT. [Methods] A ciphertext policy attribute based encryption (CPABE) scheme for power IoT scenarios based on the SM9 algorithm was proposed ...
ZHANG Yanjie   +6 more
doaj   +1 more source

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