Results 101 to 110 of about 1,357,611 (303)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Maintaining public health insurance benefits: How primary care clinics help keep low-income patients insured

Patient Experience Journal, 2017
Low-income families struggle to obtain and maintain public health insurance. We identified strategies used by Community Health Centers (CHCs) to assist patients with insurance applications, and assessed patients’ receptivity to these efforts ...
Rose Harding, Jennifer Hall, Jennifer DeVoe, Heather Angier, Rachel Gold, Christine Nelson, Sonja Likumahuwa-Ackman, John Heintzman, Aleksandra Sumic, Deborah Cohen   +9 more
doaj  

Complete gradient-LC-ESI system on a chip for protein analysis [PDF]

, 2005
This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray ionization (LC-ESI) system on a chip. This chip integrates a pair of high-pressure gradient pumps, a sample injection pump, a passive mixer, a packed ...
Lee, T. D., Shih, J., Tai, Y. C., Xie, J.   +3 more
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

A 16 Rules@2.5Mflips Mixed-Signal Programmable Fuzzy Controller CMOS-1μm Chip [PDF]

, 1996
We present a fuzzy inference chip capable to evaluate 16 programmable rules at a speed of 2.5Mflips (2.5 × 10 6 fuzzy inferences per second) with 8.6mW power consumption.
Navas González, Rafael, Rodríguez Vázquez, Ángel Benito, Vidal Verdú, Fernando   +2 more
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Viabilidad de una bacteria láctica encapsulada e incorporada en una matriz de cobertura de chocolate

Revista Colombiana de Biotecnología, 2015
Se evaluó la viabilidad durante el almacenamiento de Weissella confusa incorporada en una matriz de cobertura de chocolate. La bacteria probiótica se encapsuló empleando tres materiales de pared, gel de Aloe vera, gel Aloe vera + Almidón al 10 % y gel de
Estefania García Gonzalez, Liliana Serna Cock   +1 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Research on Intelligent Voltage Regulation Method Within a Station Based on Multi-Agent Reinforcement Learning

IEEE Access
In response to the issues that existing voltage regulation methods cannot finely perceive the load data within the station area, have low regulation precision, and often use active power regulation leading to high electricity costs for users, a novel ...
Zhe Zheng, Pan Li, Wenpeng Cui, Yu Liu, Mingyang Sun, Yingying Chi, Qingchen Yang, Yuzhe Chen   +7 more
doaj   +1 more source

Multichip packaging with thermal insulation [PDF]

, 1968
Thermal insulation technique permits low and high power electronic chips to operate in the same package without thermal cross-coupling. An alumina glass shield thermally isolates the low power chip from the high power chip while Kovar substrate acts as a
Mc Inturff, R. G., Mend, W. G.
core   +1 more source