Results 101 to 110 of about 639,557 (319)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Blind Chip-Rate Multiuser Equalisation

, 2003
This paper addresses blind multiuser detection in a DS-CDMA downlink channel. The synchronous users are separated by re-establishing orthogonality of their spreading sequences in a common chip-rate equaliser.
S. Weiss, M. Hadef, Weiss, S., Hadef, M.
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Targeting innate immune memory: a new paradigm for gout treatment [PDF]

Exploration of Musculoskeletal Diseases
Gout is a chronic inflammatory arthritis driven by monosodium urate crystal deposition and the NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome activation, leading to interleukin-1β (IL-1β)-mediated inflammation.
Orsolya I. Gaal, Leo A.B. Joosten, Tania O. Crișan   +2 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

On-Chip time measurement architectures and implementation

, 2009
In recent years, system on chip (SoC) devices have become increasingly popular in many applications, such as automotive, signal processing, portable electronic devices and communication products. This has led to more functionality being integrated onto a
Collins, Matthew
core  

Chip Wolfe

, 2021
Chip Wolfe, CTT3, US Navy Biography. Chip Wolfe served in the U.S. Navy from 1990-’94. He trained at the Naval Training Center Orlando and the Navy Technical Training Center, Corry Station in Pensacola, emerging in the intelligence field as a ...
Wolfe, Chip
core  

Technology and technique of the CMOS-chip learning experiment

Физика волновых процессов и радиотехнические системы, 2018
The technique of the learning experiment of the chips with a CMOS structure is considered. The analysis of the constructive-technological features of the 765 series chips have carried out.
R.O. Mishanov
doaj  

Research on Intelligent Voltage Regulation Method Within a Station Based on Multi-Agent Reinforcement Learning

IEEE Access
In response to the issues that existing voltage regulation methods cannot finely perceive the load data within the station area, have low regulation precision, and often use active power regulation leading to high electricity costs for users, a novel ...
Zhe Zheng, Pan Li, Wenpeng Cui, Yu Liu, Mingyang Sun, Yingying Chi, Qingchen Yang, Yuzhe Chen   +7 more
doaj   +1 more source