Results 81 to 90 of about 1,357,611 (303)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Génesis del hombre biónico y los dispositivos electrónicos

Revista de Iniciación Científica, 2018
Son evidentes los vertiginosos avances de las ciencias en el campo de la biomédica, en especial con el desarrollo de nuevos dispositivos que están sustituyendo poco a poco las funciones de algunos órganos.
Félix Cantú, Alfredo Licona, Yazmín Dorati   +2 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A high speed truly random number generator based on thermal noise oscilltor

Dianzi Jishu Yingyong, 2018
A truly random number generator based on thermal noise was proposed, and the resistance thermal noise was used as the noise source of the low frequency clock. It uses two independent working relative relationship between high and low frequency oscillator
Wei Zikui, Fu Ling, Wang Xue, He Yang, Jin Xin, Tan Lang, Hu Yi, Tang Xiaoke, Zhang Haifeng, Zhao Dongyan   +9 more
doaj   +1 more source

Robotics in space-age manufacturing [PDF]

Robotics technologies are developed to improve manufacturing of space hardware. The following applications of robotics are covered: (1) welding for the space shuttle and space station Freedom programs; (2) manipulation of high-pressure water for shuttle ...
Jones, Chip
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

A LEGISLATIVE PERSPECTIVE ON CURRENT AND FUTURE CHANGES IN U.S. FARM POLICY [PDF]

Agricultural and Food Policy,
Conley, Chip
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Hardware sollution about power fail protective mechanism of non volatile memory

Dianzi Jishu Yingyong, 2019
The principle of data power failure protection for non-volatile memory(NVM) of security chip is analyzed. Considering that the processing speed of software can not meet the performance requirements of security chip for data storage, this paper proposes a
Su Wei, Feng Xi, Zhou Zhimei, Hu Yi, Tang Xiaoke   +4 more
doaj   +1 more source

Competition on MARS? A study of broker-dealer competition in the U.S. municipal auction rate securities market [PDF]

The relationship between competitive bidding in auctions and its impact on price and interest rates has long been of importance for a wide range of market practitioners.
cole, Chip, Edwards, Jeffrey A.
core   +1 more source