Results 91 to 100 of about 1,357,611 (303)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
AER Building Blocks for Multi-Layer Multi-Chip Neuromorphic Vision Systems [PDF]
, 2005 A 5-layer neuromorphic vision processor whose components communicate spike events asychronously using the address-eventrepresentation (AER) is demonstrated.
Acosta Jiménez, Antonio José +17 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Comparison and Realization of Fast Acquisition Method for GPS Signal under High Dynamic
MATEC Web of Conferences, 2017 In order to solve the problem of fast acquisition for GPS signal under high dynamic, the paper add window in traditional Partial Matched Filter (PMF) plus Fast Fourier Transform (FFT) for fast acquisition with the purpose of reducing the scalloping loss ...
Zeng Chan +3 more
doaj +1 more source
Targeting innate immune memory: a new paradigm for gout treatment [PDF]
Exploration of Musculoskeletal DiseasesGout is a chronic inflammatory arthritis driven by monosodium urate crystal deposition and the NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome activation, leading to interleukin-1β (IL-1β)-mediated inflammation.
Orsolya I. Gaal +2 more
doaj +1 more source
Root system chip-firing II: Central-firing
, 2019 Jim Propp recently proposed a labeled version of chip-firing on a line and conjectured that this process is confluent from some initial configurations. This was proved by Hopkins-McConville-Propp. We reinterpret Propp's labeled chip-firing moves in terms
Galashin, Pavel +3 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Building an Application-specific Memory Hierarchy on FPGA [PDF]
, 2008 The high potential performance of FPGAs cannot be exploited if a design suffers a memory bottleneck. Therefore, a memory hierarchy is needed to reuse data in on-chip memories and minimize the number of accesses to off-chip ...
Devos, Harald +2 more
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Progress in atom chips and the integration of optical microcavities
, 2008 We review recent progress at the Centre for Cold Matter in developing atom chips. An important advantage of miniaturizing atom traps on a chip is the possibility of obtaining very tight trapping structures with the capability of manipulating atoms on the
Darquié, B. +4 more
core +2 more sources