Results 111 to 120 of about 5,795,971 (345)

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Evaluation of the Total Thrombus-Formation System (T-TAS): application to human and mouse blood analysis

Platelets, 2019
The Total Thrombus-formation Analyser System (T-TAS) is a whole blood flow chamber system for the measurement of in vitro thrombus formation under variable shear stress conditions.
Rashid Al Ghaithi, Jun Mori, Zoltan Nagy, Annabel Maclachlan, Lewis Hardy, Helen Philippou, Emma Hethershaw, Neil V. Morgan, Yotis A. Senis, Paul Harrison   +9 more
doaj   +1 more source

Chip Formation and Orthogonal Cutting Optimisation of Unidirectional Carbon Fibre Composites. [PDF]

Polymers (Basel), 2023
Abena A, Soo SL, Ataya S, Hassanin H, El-Sayed MA, Ahmadein M, Alsaleh NA, Ahmed MMZ, Essa K.   +8 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Modeling and analysis of the chip formation and transient cutting force during elliptical vibration cutting process

AIP Advances, 2017
In traditional diamond cutting, the cutting force is usually large and it will affect tool life and machining quality. Elliptical vibration cutting (EVC) as one of the ultra-precision machining technologies has a lot of advantages, such as reduces ...
Jieqiong Lin, Liang Guan, Mingming Lu, Jinguo Han, Yudi Kan   +4 more
doaj   +1 more source

Study on Chip Formation Mechanism of Single Crystal Copper Using Molecular Dynamics Simulations. [PDF]

Nanoscale Res Lett, 2022
Zhang P, Li X, Zhang J, Zhang Y, Huang X, Ye G.   +5 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Paper-Based Electrodeposition Chip for 3D Alginate Hydrogel Formation

Micromachines, 2015
Hydrogel has been regarded as one significant biomaterial in biomedical and tissue engineering due to its high biocompatibility. This paper proposes a novel method to pattern calcium alginate hydrogel in a 3D way via electrodeposition process based on a ...
Wenfeng Wan, Gaole Dai, Lijun Zhang, Yajing Shen   +3 more
doaj   +1 more source

A Joint Johnson-Cook-TANH Constitutive Law for Modeling Saw-Tooth Chip Formation of Ti-6AL-4V Based on an Improved Smoothed Particle Hydrodynamics Method. [PDF]

Materials (Basel), 2023
Niu W, Wang Y, Li X, Guo R.
europepmc   +1 more source