Results 121 to 130 of about 5,795,971 (345)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Influence of Machining Parameters on Cutting and Chip-Formation Process during Cortical Bone Orthogonal Machining. [PDF]

Materials (Basel), 2022
Zawadzki P, Talar R, Patalas A, Legutko S.   +3 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

FEM and Analytical Modeling of the Incipient Chip Formation for the Generation of Micro-Features. [PDF]

Materials (Basel), 2021
Lanzetta M, Gharibi A, Picchi Scardaoni M, Vivaldi C.   +3 more
europepmc   +1 more source

The Star Formation Region NGC 6530: distance, ages and Initial Mass Function

, 2004
We present astrometry and $BVI$ photometry, down to $V\simeq22$, of the very young open cluster NGC6530, obtained from observations taken with the Wide Field Imager camera at the MPG/ESO 2.2 m Telescope. Both the $V$ vs. $B-V$ and the $V$ vs. $V-I$ color-
Alcala, Alves, Baraffe, Baraffe, Bouvier, Briceño, Chabrier, Chini, Damiani, F. Damiani, Feigelson, Flaccomio, Flaccomio, G. Micela, Hiltner, Kenyon, Kilambi, L. Prisinzano, Lada, Landolt, Loktin, Loktin, Mathis, McCall, Meyer, Momany, Muench, Muench, Muench, Munari, Navascues, Randich, Rauw, S. Sciortino, Sagar, Siess, Simon, Sterzik, Stetson, Stetson, Stetson, Stetson, Sung, Sung, The, van Altena, van den Ancker, Walker, Walker   +48 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Simulation of plastic deformation and destruction in the process of chip formation

MATEC Web of Conferences, 2018
Metal cutting is a complex process in which several mechanisms are at work simultaneously. The mathematical modelling allows carrying out research into the optimization of machining conditions.
Tärgla Tanel, Olt Jüri, Liivapuu Olga
doaj   +1 more source

Prediction of Cutting Force and Chip Formation from the True Stress-Strain Relation Using an Explicit FEM for Polymer Machining. [PDF]

Polymers (Basel), 2022
Yang B, Wang H, Fu K, Wang C.
europepmc   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Machinability of Normalized and Stress-Relieved C45 Steel in Dry Internal Turning

Tribology in Industry
This experimental study provides new insights into the dry internal turning behaviour of seamless cold-drawn DIN C45 steel tubes subjected to different heat treatment conditions (normalized and stress-relieved).
Henrique Oliveira Santos, Mickaela Ramos Barbosa, Carlos Eduardo dos Santos, Marcello Rosa Dumont   +3 more
doaj   +1 more source