Results 41 to 50 of about 426 (244)

Architecture of an All‐In‐One Microfluidic Platform for Accelerated Cancer Seeding, Enhanced Spheroid Formation, and Dynamic Drug Screening Trials

open access: yesAdvanced Materials Technologies, EarlyView.
An all‐in‐one microfluidic platform consists of two‐layered PDMS channels integrated with a hydrogel microwell array. This platform enables flow‐driven tumor cell capture, enhanced spheroid formation within the microwells, and advective drug testing. ABSTRACT Effective cancer drug screening requires platforms that replicate the physiological complexity
Omar M. Rahman   +2 more
wiley   +1 more source

Koncepcja krzemieniarstwa schyłkowego na przykładzie eneolitu Moraw

open access: yesPrzegląd Archeologiczny, 2012
The concept of Terminal Lithic Industries has been developed as a result of a century-long interest of Polish archaeologists in chipped stone materials from the turn of Stone and Bronze Ages.
Jerzy Kopacz
doaj  

Transducers Across Scales and Frequencies: A System‐Level Framework for Multiphysics Integration and Co‐Design

open access: yesAdvanced Materials Technologies, EarlyView.
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu   +8 more
wiley   +1 more source

The Challenge of Characterising Large Assemblages of Exotic Materials: a case study of the obsidian from Domuztepe, SE Turkey

open access: yesInternet Archaeology, 2009
Obsidian artefacts from Domuztepe (a large late Neolithic site in the Kahramanmaraş plain in south-east Turkey belonging to the Halaf culture and dated to c. 6000-5500 cal.
Elizabeth Healey , Stuart Campbell
doaj   +1 more source

3D Printing of Soft Robotic Systems: Advances in Fabrication Strategies and Future Trends

open access: yesAdvanced Robotics Research, EarlyView.
Collectively, this review systematically examines 3D‐printed soft robotics, encompassing material selections, function integration, and manufacturing methodologies. Meanwhile, fabrication strategies are analyzed in order of increasing complexity, highlighting persistent challenges with proposed solutions.
Changjiang Liu   +5 more
wiley   +1 more source

Flint assemblages in the context of cultural transition during the 6th millennium BC: a case study from Bulgaria

open access: yesБългарско е-Списание за Археология, 2018
This paper offers a general overview of the chipped stone assemblages from Bulgaria during the Neolithic period (6th millennium BC). Based on numerous flint assemblages belonging to different phases of the Neolithic (many of them studied by the author ...
Maria Gurova
doaj  

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

open access: yesAdvanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin   +11 more
wiley   +1 more source

Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair

open access: yesAdvanced Science, EarlyView.
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz   +20 more
wiley   +1 more source

Note on a Possible Chipped Stone Grubbing Tool from Upshur County, Texas

open access: yesIndex of Texas Archaeology Open Access Grey Literature from the Lone Star State, 2005
During the period August 6-27, and November 18-20, 2003, archeologists from Geo-Marine Inc. (GMI), of Plano, Texas, conducted a pedestrian survey of a 51.5 km-long corridor for the proposed Southside Regional Water System in Marion, Harrison, Upshur, and Gregg counties, Texas.
Lintz, Christopher, Largent, Floyd
openaire   +3 more sources

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

open access: yesAdvanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian   +5 more
wiley   +1 more source

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