Results 231 to 240 of about 1,137,059 (290)

β-Cyclodextrin-Self-Assembled Nanochannel Membrane for the Separation of Chiral Drugs

open access: yesACS Applied Nano Materials, 2020
The fabrication of a membrane with the capability of chiral selective transport is a big challenge in the membrane separation of chiral drugs. To solve the problem of chiral selectivity in membrane separation, drug/metabolite transport (DMT) in the cell ...
Haibing Li
exaly   +2 more sources

Chiral Separations

Annual Review of Analytical Chemistry, 2010
The main goal of this review is to provide a brief overview of chiral separations to researchers who are versed in the area of analytical separations but unfamiliar with chiral separations. To researchers who are not familiar with this area, there is currently a bewildering array of commercially available chiral columns, chiral derivatizing reagents ...
openaire   +2 more sources

Transfer of Chirality for Memory and Separation

2010
Transfer of chirality is an intriguing issue worth studying to understand better the origin of life and for possible technological applications. In the last few years we have been working in this area studying the chain of events that begins with induction, reaches a permanent transfer (chiral memory) and extends in some cases to a (quasi-)reversible ...
R. Lauceri   +3 more
openaire   +4 more sources

The development of biphasic chiral recognition in chiral separation

Chirality, 2018
AbstractIn chiral separation, enantioseparation factor is an important parameter which influences the resolution of enantiomers. In this current overview, a biphasic chiral recognition method is introduced to the readers. This method can significantly improve the enantioseparation factor in two‐phase solvent through adding lipophilic and hydrophilic ...
Xin-Yi, Huang   +4 more
openaire   +2 more sources

Subsecond chiral separations on a microchip

ELECTROPHORESIS, 2004
AbstractFast chiral separation of DNS‐amino acids could be realized using microchip electrophoresis with fluorescence detection. For this purpose, highly sulfated cyclodextrins (HS‐γ‐CD) were used as chiral selectors enabling high selectivity. Even subsecond separation of DNS‐tryptophan, DNS‐norleucine, DNS‐phenylalanine, DNS‐methionine, and DNS ...
Piehl, N., Ludwig, M., Belder, D.
openaire   +3 more sources

SFC for chiral separations in bioanalysis

Journal of Pharmaceutical and Biomedical Analysis, 2019
This review covers literature investigating methods for enantioselective chromatography using supercritical fluids as mobile phase constituents (SFC) in the field of bioanalysis. It provides an overview on method development and screening approaches published in scientific literature 2014-2018.
Lukas C. Harps   +2 more
openaire   +2 more sources

Chiral On-Chip Separations of Neurotransmitters

Analytical Chemistry, 2003
The fast on-chip determination of a range of compounds of relevance in the study and treatment of neurological disorders is demonstrated. These include dopamine and its metabolites methoxytyramine, homovanillic acid, noradrenaline, adrenaline, normetanephrine, and metanephrine, its artificial precursors DOPA and tyrosine; and the related compounds DOPS
Schwarz MA, Hauser PC
openaire   +3 more sources

Microchip electrophoresis for chiral separations

ELECTROPHORESIS, 2003
AbstractMicrochip electrophoresis (MCE) is a promising new technique for the separation of enantiomers. This recently introduced technique enables chiral separations to be performed in seconds on tiny micromachined devices. This review is intended to give a brief introduction into the principles of chiral separations with MCE with regard to methodology
Belder, D., Ludwig, M.
openaire   +3 more sources

A Reversible Gel for Chiral Separations

Analytical Chemistry, 2004
The use of a guanosine gel as a chiral selector in capillary electrophoresis is introduced. Guanosine gels are reversible organized media that are formed through the self-association of guanosine compounds. Their degree of organization and their physicochemical properties can be modulated through variations in guanosine monomer concentration, pH ...
Victoria A, Dowling   +3 more
openaire   +2 more sources

Chiral separation of agricultural fungicides

Journal of Chromatography A, 2011
Fungicides are very important and diverse environmental and agricultural concern species. Their determination in commercial formulations or environmental matrices, requires highly efficient, selective and sensitive methods. A significant number of these chemicals are chiral with the activity residing usually in one of the enantiomers.
PEREZ FERNANDEZ, VIRGINIA   +2 more
openaire   +2 more sources

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