Results 11 to 20 of about 252,292 (239)

Evaluation and Application of Stationary Phase Selectivity for Drug Analysis [PDF]

open access: yes
Despite the wide range of HPLC stationary phases available for reversed-phase high-performance liquid chromatography (RP-HPLC) and the in-depth studies using probes to highlight differences between them, there is very little in the way of stationary ...
Perera, R. Wimal H.
core   +6 more sources

Application of Natural and Modified Biomacromolecules in Miniaturised Separative Analytical Techniques [PDF]

open access: yes
In pharmaceutical R & D, drug stereochemistry, and consequently the rotation of enantiomers, is very important. Because they act as chiral selectors in vivo, biomacromolecules have been extensively used as chiral selectors for the liquid chromatographic (
Salmon, Andrew B
core   +6 more sources

Chromatographic Studies of Protein-Based Chiral Separations. [PDF]

open access: yesSeparations, 2016
The development of separation methods for the analysis and resolution of chiral drugs and solutes has been an area of ongoing interest in pharmaceutical research.
Bi C   +5 more
europepmc   +2 more sources

Capillary Electrophoresis Mass Spectrometry: Developments and Applications for Enantioselective Analysis from 2011–2020

open access: yesMolecules, 2022
It is now more than 25 years since the first report of enantioselective analysis by capillary electrophoresis-mass spectrometry (CE-MS) appeared.
Shahab A. Shamsi, Ferdoushi Akter
doaj   +1 more source

The Way to Ultrafast, High-Throughput Enantioseparations of Bioactive Compounds in Liquid and Supercritical Fluid Chromatography

open access: yesMolecules, 2018
Until less than 10 years ago, chiral separations were carried out with columns packed with 5 or 3 μ m fully porous particles (FPPs). Times to resolve enantiomeric mixtures were easily larger than 30 min, or so.
Omar H. Ismail   +8 more
doaj   +1 more source

Application of Carbon Nanotubes in Chiral and Achiral Separations of Pharmaceuticals, Biologics and Chemicals

open access: yesNanomaterials, 2017
Carbon nanotubes (CNTs) possess unique mechanical, physical, electrical and absorbability properties coupled with their nanometer dimensional scale that renders them extremely valuable for applications in many fields including nanotechnology and ...
Ayman L. Hemasa   +3 more
doaj   +1 more source

Super/subcritical fluid chromatography with packed columns: state of the art and applications

open access: yesQuímica Nova, 2014
Separations using supercritical fluid chromatography (SFC) with packed columns have been re-discovered and explored in recent years. SFC enables fast and efficient separations and, in some cases, gives better results than high performance liquid ...
Carla Grazieli Azevedo da Silva   +1 more
doaj   +1 more source

Condensation and asymmetric amplification of chirality in achiral molecules adsorbed on an achiral surface

open access: yesNature Communications, 2023
The origin of homochirality in nature is an important but open question. Here, we demonstrate a simple organizational chiral system constructed by achiral carbon monoxide (CO) molecules adsorbed on an achiral Au(111) substrate.
Huiru Liu   +8 more
doaj   +1 more source

Cromatografia em leito móvel simulado na produção de substâncias enantiomericamente puras ou enriquecidas em larga escala

open access: yesQuímica Nova, 2006
There is great interest nowadays in the use of preparative liquid chromatography as an effective tool for the production of enantiomerically pure, or enriched, compounds for the pharmaceutical industry.
Ivanildo José da Silva Junior   +5 more
doaj   +3 more sources

Chiral separation by ligand-exchange

open access: yesMacedonian Journal of Chemistry and Chemical Engineering, 2011
The principle of chiral ligand-exchange, introduced by Davankov, has become a widely used technique for chiral separation in both chromatography and in electromigration techniques.
Martin G Schmid, Gerald Gübitz
doaj   +1 more source

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