Results 1 to 10 of about 2,584 (110)

Silica Immobilised Chloro- and Amido-Derivatives of Eremomycine as Chiral Stationary Phases for the Enantioseparation of Amino Acids by Reversed-Phase Liquid Chromatography [PDF]

open access: yesMolecules, 2022
Macrocyclic glycopeptide antibiotics immobilized on silica are one of the effective classes of stationary phases for chiral recognition and HPLC separation of a wide range of optically active compounds.
Nikita Sarvin   +4 more
doaj   +2 more sources

Chiral Separation of Cannabichromene, Cannabicyclol, and Their Acidic Analogs on Polysaccharide Chiral Stationary Phases [PDF]

open access: yesMolecules, 2023
Until recently, chirality has not been a major focus in the study of cannabinoids, as most cannabinoids of interest, such as cannabidiol and tetrahydrocannabinol, exist as a single isomer from natural sources.
John M. Ferraro, Weston J. Umstead
doaj   +2 more sources

Chiral Stationary Phases for Liquid Chromatography: Recent Developments [PDF]

open access: yesMolecules, 2019
The planning and development of new chiral stationary phases (CSPs) for liquid chromatography (LC) are considered as continuous and evolutionary issues since the introduction of the first CSP in 1938.
Joana Teixeira   +3 more
doaj   +2 more sources

The Separation of Cannabinoids on Sub-2 µm Immobilized Polysaccharide Chiral Stationary Phases [PDF]

open access: yesPharmaceuticals, 2021
The increased use and applicability of Cannabis and Cannabis-derived products has skyrocketed over the last 5 years. With more and more governing bodies moving toward medical and recreational legalization, the need for robust and reliable analytical ...
Takafumi Onishi, Weston J. Umstead
doaj   +2 more sources

New Brush-Type Chiral Stationary Phases for Enantioseparation of Pharmaceutical Drugs [PDF]

open access: yesMolecules, 2019
The importance of chirality in drug development is unquestionable, with chiral liquid chromatography (LC) being the most adequate technique for its analysis.
Anamarija Knežević   +2 more
doaj   +2 more sources

Comprehensive Review on Chiral Stationary Phases in Single-Column Simultaneous Chiral–Achiral HPLC Separation Methods [PDF]

open access: yesMolecules
This comprehensive review explores the utilization of chiral stationary phases (CSPs) in the context of single-column simultaneous chiral–achiral high-performance liquid chromatography (HPLC) separation methods. While CSPs have traditionally been pivotal
Lajos Attila Papp   +4 more
doaj   +2 more sources

Chiral Recognition for Chromatography and Membrane-Based Separations: Recent Developments and Future Prospects

open access: yesMolecules, 2021
With the rapid development of global industry and increasingly frequent product circulation, the separation and detection of chiral drugs/pesticides are becoming increasingly important. The chiral nature of substances can result in harm to the human body,
Yuan Zhao   +4 more
doaj   +1 more source

Research progress of chiral ligand exchange stationary phases in the enantiomer resolution [PDF]

open access: yesE3S Web of Conferences, 2021
The structure of chiral drugs contains at least one asymmetric center. When the enantiomers act on the human body, they are recognized by chiral receptors and enzymes in vivo, which will show different physiological effects and even adverse reactions ...
Bai Hui
doaj   +1 more source

Enantioselectivity in Drug Pharmacokinetics and Toxicity: Pharmacological Relevance and Analytical Methods

open access: yesMolecules, 2021
Enzymes, receptors, and other binding molecules in biological processes can recognize enantiomers as different molecular entities, due to their different dissociation constants, leading to diverse responses in biological processes. Enantioselectivity can
Maria Miguel Coelho   +3 more
doaj   +1 more source

Reticular materials as chiral stationary phases in chromatography

open access: yesJournal of Chromatography Open, 2021
Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) are reticular materials with outstanding physical and chemical properties.
Iván Taima-Mancera, Verónica Pino
doaj   +1 more source

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