Results 1 to 10 of about 2,821 (224)
Molecules, 2023 Comparative chiral separations of enantiomeric pairs of four oxazolidinone and two related thio-derivatives were performed by capillary electrophoresis, using cyclodextrins (CDs) as chiral selectors.
Zoltán-István Szabó +5 more
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A Look at the Importance of Chirality in Drug Activity: Some Significative Examples
Applied Sciences, 2022 Chirality plays an important role in the development of many pharmaceuticals, being a general property of ‘handedness’; nevertheless, a large number of pharmaceuticals are still marketed and administered as racemates.
Jessica Ceramella +7 more
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Chemosensors, 2021 Ketamine (K) and its main metabolite, norketamine (NK), are chiral compounds that have been found in effluents from wastewater treatment plants (WWTPs) and aquatic environments.
Ariana Pérez-Pereira +4 more
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Progress in the Enantioseparation of β-Blockers by Chromatographic Methods
Molecules, 2021 β-adrenergic antagonists (β-blockers) with at least one chiral center are an exceedingly important class of drugs used mostly to treat cardiovascular diseases. At least 70 β-blockers have been investigated in history. However, only a few β-blockers, e.g.,
Yiwen Yang +5 more
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Arhiv za Higijenu Rada i Toksikologiju, 2020 Beta-blockers are chiral compounds with enantiomers that have different bioactivity, which means that while one is active, the other can be inactive or even harmful.
Pocrnić Marijana +5 more
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Pharmaceuticals, 2022 Analytical-method development based on design of experiment has been applied for optimizing the enantioseparation of amlodipine by chiral capillary electrokinetic chromatography using maltodextrin as the chiral selector.
Ratih Ratih +3 more
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Molecules, 2013 Enantioseparation is largely based on the formation of transitional complexes, the solvation species, the stationary phase configurations or the diastereomeric complexes formed by analytes and the chiral stationary phase.
Hong-Xun Guo, Steven Wu, Jingshun Sun
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Chemosensors, 2022 Metal–organic frameworks (MOFs), as high-surface-area materials, have shown promise in various areas of application, such as chiral sensing and separation, due to their flexibility in design and organized porous cages.
Soodabeh Hassanpour +2 more
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Separation of propranolol enantiomers using chiral HPLC [PDF]
Kragujevac Journal of Science, 2023 Enantiomers of pharmaceuticals may exhibit different effects because the organism serves as a chiral selector. Enantiomers can now be identified and separated using analytical techniques such as gas chromatography and high-performance liquid ...
Turković Nemanja M. +3 more
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Pharmaceuticals, 2021 Chondroitin sulfate A was covalently immobilized onto a monolithic silica epoxy column involving a Schiff base formation in the presence of ethylenediamine as a spacer and evaluated in terms of its selectivity in enantioseparation.
Ratih Ratih +5 more
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