Results 31 to 40 of about 5,412 (216)
Progress in the Enantioseparation of β-Blockers by Chromatographic Methods
Molecules, 2021 β-adrenergic antagonists (β-blockers) with at least one chiral center are an exceedingly important class of drugs used mostly to treat cardiovascular diseases. At least 70 β-blockers have been investigated in history. However, only a few β-blockers, e.g.,
Yiwen Yang +5 more
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Molecules, 2013 Enantioseparation is largely based on the formation of transitional complexes, the solvation species, the stationary phase configurations or the diastereomeric complexes formed by analytes and the chiral stationary phase.
Hong-Xun Guo, Steven Wu, Jingshun Sun
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Arhiv za Higijenu Rada i Toksikologiju, 2020 Beta-blockers are chiral compounds with enantiomers that have different bioactivity, which means that while one is active, the other can be inactive or even harmful.
Pocrnić Marijana +5 more
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Pharmaceuticals, 2022 Analytical-method development based on design of experiment has been applied for optimizing the enantioseparation of amlodipine by chiral capillary electrokinetic chromatography using maltodextrin as the chiral selector.
Ratih Ratih +3 more
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Chiral separation by enantioselective liquid–liquid extraction [PDF]
, 2011 The literature on enantioselective liquid–liquid extraction (ELLE) spans more than half a century of research. Nonetheless, a comprehensive overview has not appeared during the past few decades.
Feringa, Ben L., +5 more
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Chemosensors, 2022 Metal–organic frameworks (MOFs), as high-surface-area materials, have shown promise in various areas of application, such as chiral sensing and separation, due to their flexibility in design and organized porous cages.
Soodabeh Hassanpour +2 more
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Nova Biotechnologica et Chimica, 2016 The HPLC by using chiral stationary phases based on macrocyclic antibiotics, dimethylphenyl carbamate cyklofructan 7 and β-cyclodextrin in terms of polar-organic separation mode (mobile phase methanol/acetonitrile/acetic acid/triethylamine) were used for
Hroboňová Katarína +2 more
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Separation of propranolol enantiomers using chiral HPLC [PDF]
Kragujevac Journal of Science, 2023 Enantiomers of pharmaceuticals may exhibit different effects because the organism serves as a chiral selector. Enantiomers can now be identified and separated using analytical techniques such as gas chromatography and high-performance liquid ...
Turković Nemanja M. +3 more
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Pharmaceuticals, 2021 Chondroitin sulfate A was covalently immobilized onto a monolithic silica epoxy column involving a Schiff base formation in the presence of ethylenediamine as a spacer and evaluated in terms of its selectivity in enantioseparation.
Ratih Ratih +5 more
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The way to ultrafast, high-throughput enantioseparations of bioactive compounds in liquid and supercritical fluid chromatography [PDF]
, 2018 Until less than 10 years ago, chiral separations were carried out with columns packed with 5 or 3 μm fully porous particles (FPPs). Times to resolve enantiomeric mixtures were easily larger than 30 min, or so.
Catani, Martina +8 more
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