Results 11 to 20 of about 3,249 (212)

Retention time prediction for chromatographic enantioseparation by quantile geometry-enhanced graph neural network

open access: yesNature Communications, 2023
The enantioseparation of chiral molecules is a crucial and challenging task in the field of experimental chemistry, often requiring extensive trial and error with different experimental settings.
Hao Xu   +3 more
doaj   +2 more sources

Completely Chiral Optical Force for Enantioseparation [PDF]

open access: yesScientific Reports, 2016
AbstractFast and reliable separation of enantiomers of chiral nanoparticles requires elimination of all the forces that are independent of the nanoparticle handedness and creation of a sufficiently strong force that either pushes different enantiomers in opposite directions or delays the diffusion of one of them with respect to the other.
Ivan D. Rukhlenko   +6 more
core   +5 more sources

HPLC Enantioseparation of Phenylcarbamic Acid Derivatives by Using Macrocyclic Chiral Stationary Phases

open access: yesNova Biotechnologica et Chimica, 2016
The HPLC by using chiral stationary phases based on macrocyclic antibiotics, dimethylphenyl carbamate cyklofructan 7 and β-cyclodextrin in terms of polar-organic separation mode (mobile phase methanol/acetonitrile/acetic acid/triethylamine) were used for
Hroboňová Katarína   +2 more
doaj   +2 more sources

Unveiling the Power of Computational Tools in Chiral Liquid Chromatography [PDF]

open access: yesMolecules
Chiral liquid chromatography (cLC) using chiral stationary phases (CSPs) has become a crucial technique for separating enantiomers. Understanding enantiomeric discrimination is essential for improving chromatographic conditions and elucidating chiral ...
Rita Lima   +4 more
doaj   +2 more sources

Isolation, Characterization, and Stability Assessment of Pure Enantiomers of Cathinone Derivatives via Semi-Preparative HPLC-UV Using a Phenomenex Lux® 5 Column [PDF]

open access: yesMolecules
In addition to well-known traditional synthetic illicit drugs like cocaine, amphetamines, and heroin, an increasing number of new psychoactive substances (NPS) are appearing on the global drug market.
Stefanie Handl   +3 more
doaj   +2 more sources

Possible Enantioseparation of Racemic Ribose on Chiral Surface Formed by Adsorption of Nucleobases [PDF]

open access: yesLife
The paper proposes a putative prebiotic scenario leading to homochirality in the RNA world. In this scenario, racemic ribose, the only chiral moiety in RNA, was enantioseparated (in its pyranose form) on a chiral surface formed by the adsorption of ...
Roman Bielski, Michal Tencer
doaj   +2 more sources

Enantioseparation of 5,5′-Dibromo-2,2′-dichloro-3-selanyl-4,4′-bipyridines on Polysaccharide-Based Chiral Stationary Phases: Exploring Chalcogen Bonds in Liquid-Phase Chromatography

open access: yesMolecules, 2021
The chalcogen bond (ChB) is a noncovalent interaction based on electrophilic features of regions of electron charge density depletion (σ-holes) located on bound atoms of group VI.
Paola Peluso   +10 more
doaj   +1 more source

Enantioseparation of syn- and anti-3,5-Disubstituted Hydantoins by HPLC and SFC on Immobilized Polysaccharides-Based Chiral Stationary Phases

open access: yesSeparations, 2022
The enantioseparation of syn- and anti-3,5-disubstituted hydantoins 5a–i was investigated on three immobilized polysaccharide-based columns (CHIRAL ART Amylose-SA, CHIRAL ART Cellulose-SB, CHIRAL ART Cellulose-SC) by high performance liquid ...
Mladenka Jurin   +3 more
doaj   +1 more source

Bound States in the Continuum in All‐Dielectric Metasurface: Separation of Sub‐10 nm Enantiomers

open access: yesAdvanced Photonics Research, 2022
Enantioseparation is crucial in pharmaceutics and agrochemicals. Compared to the current chemical technique, the optical enantioseparation is more effective means yet hampered by the weak chiral optical force. Recently, plasmonic nanostructures have been
Libang Mao   +7 more
doaj   +1 more source

Stationary phases based on the nanoparticles for pharmaceutical and biomolecule separations [PDF]

open access: yesNanochemistry Research, 2021
Because of impossibility to achieve a general column for separation purposes, columns must be amended in order to acquire specific chemical characteristics such as hydrophobic, hydrophilic or ionic interactions.
Forough Karami, Somayeh Karami
doaj   +1 more source

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