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The enantioseparation of chiral molecules is a crucial and challenging task in the field of experimental chemistry, often requiring extensive trial and error with different experimental settings.
Hao Xu +3 more
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Completely Chiral Optical Force for Enantioseparation [PDF]
AbstractFast and reliable separation of enantiomers of chiral nanoparticles requires elimination of all the forces that are independent of the nanoparticle handedness and creation of a sufficiently strong force that either pushes different enantiomers in opposite directions or delays the diffusion of one of them with respect to the other.
Ivan D. Rukhlenko +6 more
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The HPLC by using chiral stationary phases based on macrocyclic antibiotics, dimethylphenyl carbamate cyklofructan 7 and β-cyclodextrin in terms of polar-organic separation mode (mobile phase methanol/acetonitrile/acetic acid/triethylamine) were used for
Hroboňová Katarína +2 more
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Unveiling the Power of Computational Tools in Chiral Liquid Chromatography [PDF]
Chiral liquid chromatography (cLC) using chiral stationary phases (CSPs) has become a crucial technique for separating enantiomers. Understanding enantiomeric discrimination is essential for improving chromatographic conditions and elucidating chiral ...
Rita Lima +4 more
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Isolation, Characterization, and Stability Assessment of Pure Enantiomers of Cathinone Derivatives via Semi-Preparative HPLC-UV Using a Phenomenex Lux® 5 Column [PDF]
In addition to well-known traditional synthetic illicit drugs like cocaine, amphetamines, and heroin, an increasing number of new psychoactive substances (NPS) are appearing on the global drug market.
Stefanie Handl +3 more
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Possible Enantioseparation of Racemic Ribose on Chiral Surface Formed by Adsorption of Nucleobases [PDF]
The paper proposes a putative prebiotic scenario leading to homochirality in the RNA world. In this scenario, racemic ribose, the only chiral moiety in RNA, was enantioseparated (in its pyranose form) on a chiral surface formed by the adsorption of ...
Roman Bielski, Michal Tencer
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The chalcogen bond (ChB) is a noncovalent interaction based on electrophilic features of regions of electron charge density depletion (σ-holes) located on bound atoms of group VI.
Paola Peluso +10 more
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The enantioseparation of syn- and anti-3,5-disubstituted hydantoins 5a–i was investigated on three immobilized polysaccharide-based columns (CHIRAL ART Amylose-SA, CHIRAL ART Cellulose-SB, CHIRAL ART Cellulose-SC) by high performance liquid ...
Mladenka Jurin +3 more
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Bound States in the Continuum in All‐Dielectric Metasurface: Separation of Sub‐10 nm Enantiomers
Enantioseparation is crucial in pharmaceutics and agrochemicals. Compared to the current chemical technique, the optical enantioseparation is more effective means yet hampered by the weak chiral optical force. Recently, plasmonic nanostructures have been
Libang Mao +7 more
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Stationary phases based on the nanoparticles for pharmaceutical and biomolecule separations [PDF]
Because of impossibility to achieve a general column for separation purposes, columns must be amended in order to acquire specific chemical characteristics such as hydrophobic, hydrophilic or ionic interactions.
Forough Karami, Somayeh Karami
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