Results 11 to 20 of about 3,397 (210)

HPLC Enantioseparation of Phenylcarbamic Acid Derivatives by Using Macrocyclic Chiral Stationary Phases

Nova Biotechnologica et Chimica, 2016
The HPLC by using chiral stationary phases based on macrocyclic antibiotics, dimethylphenyl carbamate cyklofructan 7 and β-cyclodextrin in terms of polar-organic separation mode (mobile phase methanol/acetonitrile/acetic acid/triethylamine) were used for
Hroboňová Katarína, Lehotay Jozef, Čižmárik Jozef   +2 more
doaj   +2 more sources

Chromatographic and spectroscopic studies on β-cyclodextrin functionalized ionic liquid as chiral stationary phase: Enantioseparation of NSAIDs

Adsorption Science & Technology, 2018
Recently, we reported a new chiral stationary phase prepared using β-cyclodextrin functionalized with aromatic ionic liquid which is aimed to enhance the performance of enantioseparation of flavonoids and β-blockers.
Nurul Yani Rahim, Kheng Soo Tay, Sharifah Mohamad   +2 more
doaj   +2 more sources

Completely Chiral Optical Force for Enantioseparation [PDF]

Scientific Reports, 2016
AbstractFast and reliable separation of enantiomers of chiral nanoparticles requires elimination of all the forces that are independent of the nanoparticle handedness and creation of a sufficiently strong force that either pushes different enantiomers in opposite directions or delays the diffusion of one of them with respect to the other.
Ivan D. Rukhlenko, Nikita V. Tepliakov, Anvar S. Baimuratov, Semen A. Andronaki, Yurii K. Gun’ko, Alexander V. Baranov, Anatoly V. Fedorov   +6 more
core   +5 more sources

Application of threo-2-amino-1,2-diphenylethanol as a Resolving Agent for Racemic Carboxylic Acids via Diastereomeric Salt Formation. [PDF]

Chirality
The ability of threo‐2‐amino‐1,2‐diphenylethanol as a resolving agent for carboxylic acids via diastereomeric salt formation was investigated. It exhibited complementary performance to its erythro‐isomer and ortho‐halogenated mandelic acids were efficiently separated.
Kodama K, Katayama K, Hirose T.
europepmc   +2 more sources

Coated and Immobilized Polysaccharides-Based Stationary Phases for Planar Metallocenes Enantioseparation in Liquid Chromatography. [PDF]

Electrophoresis
This study examined 21 new ferrocene and ruthenocene derivatives, including those with planar and central chirality. Their stereochemical behavior was examined using UV‐detected normal‐phase liquid chromatography. Under fixed conditions, eight polysaccharide‐based chiral stationary phases were tested using n‐heptane combined with either 2‐propanol or ...
Wartelle F, Leblond R, Bonin L, Ghinet A, Lipka E.   +4 more
europepmc   +2 more sources

Protein-Based High-Performance Liquid Chromatography and Cyclodextrin-Capillary Electrokinetic Chromatography for the Chiral Separation of Azoles. [PDF]

Electrophoresis
Human serum albumin‐based high‐performance liquid chromatography and cyclodextrin‐based capillary electrokinetic chromatography were used for the chiral separation of azoles. Although only two of the five tested azoles could be enantioseparated by liquid chromatography, all of them were separated by capillary electrokinetic chromatography using single ...
Moreau S, Dillon A, Russo G, Wiedmer SK.
europepmc   +2 more sources

Green Chiral HPLC Method for Lumefantrine Analysis: Method Development, Greenness Assessment, and Computational Studies. [PDF]

Chirality
A green chiral HPLC method was developed and validated for the determination of lumefantrine enantiomers. The method employs ethanol as a mobile phase as a sustainable and efficient alternative to hexane. The chiral recognition mechanism and elution order of the enantiomers were investigated using electronic circular dichroism and molecular docking ...
Mohr A, das Neves GM, Segala É, Eifler-Lima VL, Steppe M.   +4 more
europepmc   +2 more sources

Determination of Enantiomers of Deschloroketamine and Its Metabolites in Wistar Rat Brains. [PDF]

J Sep Sci
Although supercritical fluid chromatography coupled to mass spectrometry efficiently resolved deschlorketamine and its metabolites, the parent drug must have been quantified by capillary zone electrophoresis. ABSTRACT Deschloroketamine (DXE) is a dissociative new psychoactive substance whose enantiomers and metabolites may exhibit distinct ...
Paškanová N, Hrubá V, Frühauf P, Jurásek B, Kuchař M, Řezanka P, Kohout M.   +6 more
europepmc   +2 more sources

Chiral HPLC Separation of Phosphonothrixin and Phosphonate Derivatives and Electronic Circular Dichroism Characterization of the Isolated Enantiomers. [PDF]

Electrophoresis
Natural compound phosphonothrixin's herbicidal activity resides exclusively in its (S)‐enantiomer, yet existing enantioselective syntheses are cumbersome, and direct chiral LC separation is hampered by the compound's high polarity, lack of aromatic groups, and metal chelation–induced peak tailing.
Maalouf M, Knab M, Gessner L, Engelhardt M, Friedrich S, Gross H, Boeckler F, Hughes CC, Lämmerhofer M.   +8 more
europepmc   +2 more sources

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis-Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis. [PDF]

Electrophoresis
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Scriba GKE.
europepmc   +2 more sources