Results 21 to 30 of about 3,397 (210)

In-situ and one-step preparation of protein film in capillary column for open tubular capillary electrochromatography enantioseparation [PDF]

, 2021
In this work, the phase-transitioned BSA (PTB) film using the mild and fast fabrication process adhered to the capillary inner wall uniformly and the fabricated PTB film-coated capillary column was applied to realize open tubular capillary ...
Anne Manyande, Manyande, Anne, Shengda Qi, Li, L, Ling Li, Huige Zhang, Qi, X, Wenjuan Lv, Hongli Chen, Hongying Du, Xue, X, Xuqi Xue, Du, H, Lv, W, Zhang, H, Chen, H   +15 more
core   +1 more source

Enantioselective HPLC of Liquid Crystals Bearing a Small and Flexible 2‐Methylbutyl Chiral Center [PDF]

J Sep Sci
Enantioseparation of liquid crystalline compounds with a 2‐methylbutyl chiral center is studied on two amylose chiral stationary phases in polar organic and reversed‐phase mode. The effects of mobile phase composition and of the solutes‘ structure on their chromatographic behavior is discussed. All compounds were baseline separated.
Jurkovičová T, Cigl M, Hamplová V, Novotná V, Vaňkátová P.   +4 more
europepmc   +2 more sources

Comparative Chiral Separation of Thalidomide Class of Drugs Using Polysaccharide-Type Stationary Phases with Emphasis on Elution Order and Hysteresis in Polar Organic Mode

Molecules, 2021
The enantioseparation of four phthalimide derivatives (thalidomide, pomalidomide, lenalidomide and apremilast) was investigated on five different polysaccharide-type stationary phases (Chiralpak AD, Chiralpak AS, Lux Amylose-2, Chiralcel OD and Chiralcel
Mohammadhassan Foroughbakhshfasaei, Máté Dobó, Francisc Boda, Zoltán-István Szabó, Gergő Tóth   +4 more
doaj   +1 more source

Enantioseparation of 3-Hydroxycarboxylic Acids via Diastereomeric Salt Formation by 2-Amino-1,2-diphenylethanol (ADPE) and Cinchonidine

Molecules, 2022
Enantioseparation of 3-hydroxycarboxylic acids via diastereomeric salt formation was demonstrated using 2-amino-1,2-diphenylethanol (ADPE) and cinchonidine as the resolving agents.
Srinivas Chandrasekaran, Masaki Tambo, Yuta Yamazaki, Tatsuro Muramatsu, Yusuke Kanda, Takuji Hirose, Koichi Kodama   +6 more
doaj   +1 more source

Macrocyclic glycopeptide‐based chiral selectors for enantioseparation in sub/supercritical fluid chromatography

Analytical Science Advances, 2021
Increasing number of reported works dealing with macrocyclic glycopeptide‐based columns in sub/supercritical fluid chromatography (SFC) points to the growing interest in this area.
Denisa Folprechtová, Květa Kalíková
doaj   +1 more source

Polydopamine-Assisted Rapid One-Step Immobilization of L-Arginine in Capillary as Immobilized Chiral Ligands for Enantioseparation of Dansyl Amino Acids by Chiral Ligand Exchange Capillary Electrochromatography

Molecules, 2021
Herein, a novel L-arginine (L-Arg)-modified polydopamine (PDA)-coated capillary (PDA/L-Arg@capillary) was firstly fabricated via the basic amino-acid-induced PDA co-deposition strategy and employed to constitute a new chiral ligand exchange capillary ...
Yuanqi Gui, Baian Ji, Gaoyi Yi, Xiuju Li, Kailian Zhang, Qifeng Fu   +5 more
doaj   +1 more source

woshixuhao/Retention-Time-Prediction-for-Chromatographic-Enantioseparation: Retention-Time-Prediction-for-Chromatographic-Enantioseparation

, 2023
Code for Retention Time Prediction for Chromatographic Enantioseparation by Quantile Geometry-based Graph Neural ...
woshixuhao
core   +1 more source

Enantioseparation of P-Stereogenic 1-Adamantyl Arylthiophosphonates and Their Stereospecific Transformation to 1-Adamantyl Aryl-H-phosphinates

Molecules, 2023
A focused library of 1-adamantyl arylthiophosphonates was prepared in racemic form. An enantioseparation method was developed for P-stereogenic thiophosphonates using (S)-1-phenylethylamine as the resolving agent. Under optimized conditions, three out of
Bence Varga, Levente Buna, Daniella Vincze, Tamás Holczbauer, Béla Mátravölgyi, Elemér Fogassy, György Keglevich, Péter Bagi   +7 more
doaj   +1 more source

Chiral Separation of Oxazolidinone Analogs by Capillary Electrophoresis Using Anionic Cyclodextrins as Chiral Selectors: Emphasis on Enantiomer Migration Order

Molecules, 2023
Comparative chiral separations of enantiomeric pairs of four oxazolidinone and two related thio-derivatives were performed by capillary electrophoresis, using cyclodextrins (CDs) as chiral selectors.
Zoltán-István Szabó, Francisc Boda, Béla Fiser, Máté Dobó, Levente Szőcs, Gergő Tóth   +5 more
doaj   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods. [PDF]

Chirality
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Karayavuz B, Kirmizioglu CK.
europepmc   +2 more sources