Results 21 to 30 of about 3,249 (212)

Comparative Chiral Separation of Thalidomide Class of Drugs Using Polysaccharide-Type Stationary Phases with Emphasis on Elution Order and Hysteresis in Polar Organic Mode

Molecules, 2021
The enantioseparation of four phthalimide derivatives (thalidomide, pomalidomide, lenalidomide and apremilast) was investigated on five different polysaccharide-type stationary phases (Chiralpak AD, Chiralpak AS, Lux Amylose-2, Chiralcel OD and Chiralcel
Mohammadhassan Foroughbakhshfasaei, Máté Dobó, Francisc Boda, Zoltán-István Szabó, Gergő Tóth   +4 more
doaj   +1 more source

Enantioseparation of 3-Hydroxycarboxylic Acids via Diastereomeric Salt Formation by 2-Amino-1,2-diphenylethanol (ADPE) and Cinchonidine

Molecules, 2022
Enantioseparation of 3-hydroxycarboxylic acids via diastereomeric salt formation was demonstrated using 2-amino-1,2-diphenylethanol (ADPE) and cinchonidine as the resolving agents.
Srinivas Chandrasekaran, Masaki Tambo, Yuta Yamazaki, Tatsuro Muramatsu, Yusuke Kanda, Takuji Hirose, Koichi Kodama   +6 more
doaj   +1 more source

Macrocyclic glycopeptide‐based chiral selectors for enantioseparation in sub/supercritical fluid chromatography

Analytical Science Advances, 2021
Increasing number of reported works dealing with macrocyclic glycopeptide‐based columns in sub/supercritical fluid chromatography (SFC) points to the growing interest in this area.
Denisa Folprechtová, Květa Kalíková
doaj   +1 more source

Polydopamine-Assisted Rapid One-Step Immobilization of L-Arginine in Capillary as Immobilized Chiral Ligands for Enantioseparation of Dansyl Amino Acids by Chiral Ligand Exchange Capillary Electrochromatography

Molecules, 2021
Herein, a novel L-arginine (L-Arg)-modified polydopamine (PDA)-coated capillary (PDA/L-Arg@capillary) was firstly fabricated via the basic amino-acid-induced PDA co-deposition strategy and employed to constitute a new chiral ligand exchange capillary ...
Yuanqi Gui, Baian Ji, Gaoyi Yi, Xiuju Li, Kailian Zhang, Qifeng Fu   +5 more
doaj   +1 more source

Enantioseparation of P-Stereogenic 1-Adamantyl Arylthiophosphonates and Their Stereospecific Transformation to 1-Adamantyl Aryl-H-phosphinates

Molecules, 2023
A focused library of 1-adamantyl arylthiophosphonates was prepared in racemic form. An enantioseparation method was developed for P-stereogenic thiophosphonates using (S)-1-phenylethylamine as the resolving agent. Under optimized conditions, three out of
Bence Varga, Levente Buna, Daniella Vincze, Tamás Holczbauer, Béla Mátravölgyi, Elemér Fogassy, György Keglevich, Péter Bagi   +7 more
doaj   +1 more source

woshixuhao/Retention-Time-Prediction-for-Chromatographic-Enantioseparation: Retention-Time-Prediction-for-Chromatographic-Enantioseparation

, 2023
Code for Retention Time Prediction for Chromatographic Enantioseparation by Quantile Geometry-based Graph Neural ...
woshixuhao
core   +1 more source

Chiral Separation of Oxazolidinone Analogs by Capillary Electrophoresis Using Anionic Cyclodextrins as Chiral Selectors: Emphasis on Enantiomer Migration Order

Molecules, 2023
Comparative chiral separations of enantiomeric pairs of four oxazolidinone and two related thio-derivatives were performed by capillary electrophoresis, using cyclodextrins (CDs) as chiral selectors.
Zoltán-István Szabó, Francisc Boda, Béla Fiser, Máté Dobó, Levente Szőcs, Gergő Tóth   +5 more
doaj   +1 more source

Unravelling dispersion forces in liquid-phase enantioseparation. Part I: Impact of ferrocenyl versus phenyl groups [PDF]

, 2023
Background: Highly ordered chiral secondary structures as well as multiple (tunable) recognition sites are the keys to success of polysaccharide carbamate-based chiral selectors in enantioseparation science. Hydrogen bonds (HBs), dipole-dipole, and &
Mireia Pérez-Baeza, Paola Peluso, Sergio Cossu, Sechi, Barbara, Pérez-Baeza, Mireia, Barbara Sechi, Roberto Dallocchio, Peluso, Paola, Dessì, Alessandro, Chankvetadze, Bezhan, Tsetskhladze, Nutsa, Bezhan Chankvetadze, Nutsa Tsetskhladze, Giorgi Jibuti, Victor Mamane, Jibuti, Giorgi, Dallocchio, Roberto, Mamane, Victor, Alessandro Dessì, Cossu, Sergio   +19 more
core   +1 more source

Enantioseparation of new axially chiral carboxylic acids on polysaccharide-based chiral stationary phases under normal phase elution conditions

Journal of Pharmaceutical and Biomedical Analysis Open, 2023
In the last decade, the availability of new and versatile synthetic strategies for the preparation of substituted 4,4’-bipyridyl derivatives based on chemo- and regioselective functionalization of the 4,4’-bipyridine core has encouraged studies for ...
Barbara Sechi, Victor Mamane, Roberto Dallocchio, Alessandro Dessì, Sergio Cossu, Giorgi Jibuti, Paola Peluso   +6 more
doaj   +1 more source

Enantioseparation of (±)-trans-β-lactam Ureas by Supercritical Fluid Chromatography [PDF]

, 2020
In this study the enantioseparation of (±)-trans-β-lactam ureas 1a–g by supercritical fluid chromatography (SFC) was examined using different polysaccharide based chiral stationary phases (CSPs), and CO2/alcohol (70:30, V/V) as the mobile phase.
Jurin, Mladenka, Dražić, Tonko, Roje, Marin, Kontrec, Darko   +3 more
core   +1 more source