Results 41 to 50 of about 2,821 (224)

A New C₂-Symmetric Atropisomeric Thiophene-Based Monomer for Inherently Chiral Electroactive Materials: Synthesis, HPLC Resolution, and Absolute Configuration Assignment

Applied Sciences, 2023
Herein, we report on the synthesis and high-performance liquid chromatography (HPLC) resolution of a new atropisomeric C2-symmetry chiral monomer based on the 3,3′-bithiophene core, which was developed to produce novel, inherently oligomeric chiral ...
Alessia Rosetti, Giulio Apolloni, Claudio Villani, Tiziana Benincori, Roberto Cirilli   +4 more
doaj   +1 more source

Molecular Dynamics Simulations of Amylose- and Cellulose-Based Selectors and Related Enantioseparations in Liquid Phase Chromatography

Molecules, 2023
In the last few decades, theoretical and technical advancements in computer facilities and computational techniques have made molecular modeling a useful tool in liquid-phase enantioseparation science for exploring enantioselective recognition mechanisms
Roberto Dallocchio, Alessandro Dessì, Barbara Sechi, Paola Peluso   +3 more
doaj   +1 more source

Probing Chiral Recognition on Amylose Tris(3,5‐Dimethylphenylcarbamate) Using Cinnamyl 2‐Aminoanilides: The Subtle Impact of Aliphatic Substituents

ELECTROPHORESIS, EarlyView.
This study investigates how subtle aliphatic substituent differences in racemic cinnamyl 2‐aminoanilides affect chiral recognition on amylose tris(3,5‐dimethylphenylcarbamate). Pronounced enantioselectivity changes arose from minimal structural variations. Mobile phase effects were examined, with 2‐propanol improving resolution.
Selen Gözde Kaya, Alessia Raucci, Clemens Zwergel, Antonello Mai, Sergio Valente, Roberto Cirilli   +5 more
wiley   +1 more source

In-situ and one-step preparation of protein film in capillary column for open tubular capillary electrochromatography enantioseparation [PDF]

, 2021
In this work, the phase-transitioned BSA (PTB) film using the mild and fast fabrication process adhered to the capillary inner wall uniformly and the fabricated PTB film-coated capillary column was applied to realize open tubular capillary ...
Anne Manyande, Manyande, Anne, Shengda Qi, Li, L, Ling Li, Huige Zhang, Qi, X, Wenjuan Lv, Hongli Chen, Hongying Du, Xue, X, Xuqi Xue, Du, H, Lv, W, Zhang, H, Chen, H   +15 more
core   +1 more source

On the effect of aqueous organic mobile phases on the enantioseparation of halogenated 4,4’-bipyridines using polysaccharide carbamate-based chiral columns

Journal of Chromatography Open
In the last decade, the contribution of halogen bond (HaB) in liquid phase enantioseparation of halogenated analytes was demonstrated by using polysaccharide-based chiral stationary phases (CSPs) and n-hexane-containing mixtures as mobile phases.
Barbara Sechi, Giorgi Jibuti, Roberto Dallocchio, Sergio Cossu, Bezhan Chankvetadze, Victor Mamane, Paola Peluso   +6 more
doaj   +1 more source

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis—Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis

ELECTROPHORESIS, EarlyView.
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley   +1 more source

Protein‐Based High‐Performance Liquid Chromatography and Cyclodextrin‐Capillary Electrokinetic Chromatography for the Chiral Separation of Azoles

ELECTROPHORESIS, EarlyView.
Human serum albumin‐based high‐performance liquid chromatography and cyclodextrin‐based capillary electrokinetic chromatography were used for the chiral separation of azoles. Although only two of the five tested azoles could be enantioseparated by liquid chromatography, all of them were separated by capillary electrokinetic chromatography using single ...
Sarah Moreau, Amy Dillon, Giacomo Russo, Susanne K. Wiedmer   +3 more
wiley   +1 more source

Single Isomer N-Heterocyclic Cyclodextrin Derivatives as Chiral Selectors in Capillary Electrophoresis

Molecules, 2021
In order to better understand the chiral recognition mechanisms of positively charged cyclodextrin (CD) derivatives, the synthesis, the pKa determination by 1H nuclear magnetic resonance (NMR)-pH titration and a comparative chiral capillary ...
Ida Fejős, Eszter Kalydi, Edit Luca Kukk, Mimimorena Seggio, Milo Malanga, Szabolcs Béni   +5 more
doaj   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

A Review on Medicinal Chemistry and Biological Activity of Dihydropyrimidinones Against HIV

Archiv der Pharmazie, Volume 359, Issue 4, April 2026.
This article presents the latest advances in the development of dihydropyrimidinone (DHPM) derivatives as promising candidates against HIV. By exploring their interactions with essential viral targets and highlighting innovative compounds with potent antiviral activity, we provide an updated perspective on the opportunities for new antiretroviral ...
Debora I. Leite, Fernando B. Macedo, Murilo Marinho de C. Lima, Isabelle S. Brum, Jonathan Fragoso Miranda de Oliveira, Ana Clara S. Costa, Stella C. Duarte, Sarah Moon, Stefany de Castro B. Moura, Andressa P. de Oliveira, Nubia Boechat, Monica M. Bastos   +11 more
wiley   +1 more source