Results 61 to 70 of about 3,249 (212)

A Comparative Study of Coupled Preferential Crystallizers for the Efficient Resolution of Conglomerate-Forming Enantiomers

Pharmaceutics, 2017
The separation of enantiomers is of great importance due to their possible differences in therapeutic properties. Preferential crystallization in various configurations of coupled batch crystallizers is used as an attractive means to separate the ...
Aniruddha Majumder, Zoltan K. Nagy
doaj   +1 more source

Enantioseparation by Sonochromatography

Bulletin of the Korean Chemical Society, 2006
Although chiral separation has been one of the main topics of chromatographic practice for over twenty-five years, it still presents many difficulties. In this work, the ultrasonic dependence of chiral resolution was investigated at various temperatures to improve resolution and reduce analysis time.
openaire   +2 more sources

Enhanced Enantioselective Optical Trapping Enabled by Longitudinal Mie Resonances in Silicon Nanodisks

Nanophotonics, Volume 15, Issue 14, 27 July 2026.
Longitudinal Mie resonances in silicon nanodisks, excited by an azimuthally–radially polarized beam, generate strong optical chirality gradients with minimal achiral background. Magnetic quadrupole modes enable selective enantiomer trapping, achieving predicted selectivities over 100 for |κ|≥0.03 $\vert \kappa \vert \ge 0.03$ and robust performance ...
Guillermo Serrera, Pablo Albella
wiley   +1 more source

High-Performance Liquid Chromatographic Enantioseparation of Atropisomeric Biphenyls on Seven Chiral Stationary Phases

, 2011
The HPLC enantioseparation of eight racemic atropisomeric biphenyls on commercially available polymeric Chiralcel OD-H, Lux Cellulose-1, Lux Cellulose-2, Chiralcel OJ, Lux Amylose-2 and Chiralpak OT(+) and on the brush-type Whelk-O1 columns, both in ...
Zambrano V., COSSU, Sergio Antonio, Fabbri D., Delogu G., Dettori M. A., Cossu S., Peluso P.   +6 more
core   +1 more source

Engineering Homochiral Dinuclear Ir(III)-Metallohelix-Based Porous Molecular Crystals for Atropisomer Enantioseparation

, 2022
Porous molecular crystal materials offer promising applications for enantioselective separation and asymmetric catalysis, while regulating the chiral channel environment remains challenging yet.
Rong Zhang (44942), Jinguo Wu (11434248), Zhuolin Shi (7376462), Liyong Chen (78992), Xuezhao Li (2045284), Chunying Duan (1341063), Cheng He (250559), Pengyan Wu (1468912)   +7 more
core   +1 more source

Enantioseparation by Dual-flow Countercurrent Extraction: Its Application to the Enantioseparation of (.+-.)-Propranolol.

Chemical and Pharmaceutical Bulletin, 1996
Enantioseparation of (±)-propranolol has been demonstrated by countercurrent extraction with a two-phase system composed of a chloroform solution of didodecyl L-tartrate (100mM) and an acetate buffer (50mM, pH 4.4) containing boric acid (100mM). The free base of (±)-propranolol (1.6g) was dissolved in the aqueous phase and extracted five times by means
ABE, Yoshiohiro, SHOJI, Tomoko, FUKUI, Shikie, SASAMOTO, Maki, NISHIZAWA, Hideyuki   +4 more
openaire   +2 more sources

Chiral Stationary Phases and their Relationship with Enantiomer Structures in Enantioseparation Research of Analytical Laboratory

, 2017
Chiral stationary phases (CSPs) and molecular structure of enantiomers are two independent but related aspects in enantioseparation, which are discussed on the basis of the experimental data from the previous study.
Shun Yao
core   +1 more source

A Review on Medicinal Chemistry and Biological Activity of Dihydropyrimidinones Against HIV

Archiv der Pharmazie, Volume 359, Issue 4, April 2026.
This article presents the latest advances in the development of dihydropyrimidinone (DHPM) derivatives as promising candidates against HIV. By exploring their interactions with essential viral targets and highlighting innovative compounds with potent antiviral activity, we provide an updated perspective on the opportunities for new antiretroviral ...
Debora I. Leite, Fernando B. Macedo, Murilo Marinho de C. Lima, Isabelle S. Brum, Jonathan Fragoso Miranda de Oliveira, Ana Clara S. Costa, Stella C. Duarte, Sarah Moon, Stefany de Castro B. Moura, Andressa P. de Oliveira, Nubia Boechat, Monica M. Bastos   +11 more
wiley   +1 more source

Evaluation and comparison of N-cycloalkylformylated chitosan bis(arylcarbamate)s as chiral selectors for enantioseparation

, 2017
In order to systematically investigate the structural dependence on the properties of N-cycloalkyl-formylated chitosan bis(arylcarbamate)s, 3,5-dimethylphenylcarbamates of N-cyclopropylformylated, N-cyclobutylformylated, N-cyclopentylformylated and N ...
Zheng-Wu Bai, Tang, Sheng, Ke-Qin Fu, Bai, Zheng-Wu, Shao-Hua Huang, Huang, Shao-Hua, Chen, Wei, Fu, Ke-Qin, Liu, Jian-De, Xiao-Chen Wang, Jian-De Liu, Sheng Tang, Fei Yang, Wei Chen, Wang, Xiao-Chen, Yang, Fei   +15 more
core   +1 more source

Original enantioseparation of illicit fentanyls with cellulose-based chiral stationary phases under polar-ionic conditions

, 2021
Fentanyl analogues used in therapy and a range of highly potent non-pharmaceutical fentanyl derivatives are subject to international control, as the latter are increasingly being synthesized illicitly and sold as ‘synthetic heroin’, or mixed with heroin.
Cirrincione M., Protti M., Varfaj I., Mercolini L., Sardella R., Carotti A.   +5 more
core   +1 more source