Results 71 to 80 of about 3,249 (212)

The enantioselective potential of amylose tris(3‑chloro-5-methylphenyl carbamate)-based chiral stationary phase in sub/supercritical fluid and normal phase liquid chromatography

Journal of Chromatography Open
The enantioselective potential of amylose tris (3‑chloro-5-methylphenylcarbamate) based chiral stationary phase in sub/supercritical fluid chromatography and normal phase liquid chromatography was evaluated.
Denisa Folprechtová, Patricia Maestro Martínez, Květa Kalíková   +2 more
doaj   +1 more source

Wireless Enantioselective Bipolar Electrocatalysis: Visual Quantification of Chiral Tryptophan via Kinetic pH‐Transduction

ChemCatChem, Volume 18, Issue 7, 14 April 2026.
A direct chiral recognition and quantitative enantiomeric excess (ee) evaluation is achieved using an enantiopure polymer‐modified bipolar electrode. The wireless approach is controlled by the enantiomer oxidation kinetics, translating the ee into a precisely correlated, visually quantifiable pH‐induced color halo size.
Sara Grecchi, Serena Arnaboldi
wiley   +1 more source

Bis-Indole Derivatives for Polysaccharide Compositional Analysis and Chiral Resolution of D-, L-Monosaccharides by Ligand Exchange Capillary Electrophoresis Using Borate-Cyclodextrin as a Chiral Selector

Molecules, 2011
A series of aldo-bis-indole derivatives (aldo-BINs) was prepared by aromatic C-alkylation reactions of aldoses and indole in acetic acid solution. Common monosaccharides such as glucose, mannose, galactose, fucose, xylose, rhamnose, ribose, arabinose and
Wen-Bin Yang, Yin-Chen Liu, Kuo-Shiang Liao, Chien-Yuan Kuo   +3 more
doaj   +1 more source

Improved Achiral and Chiral HPLC-UV Analysis of Ruxolitinib in Two Different Drug Formulations

Separations, 2020
In this paper, two new reversed-phase (RP) HPLC-UV methods enabling the quantitative achiral and chiral analysis of ruxolitinib in commercial tablets (containing 20 mg of active pharmaceutical ingredient, API) and not commercially available galenic ...
Alessandro Di Michele, Aurélie Schoubben, Ina Varfaj, Alessandro D’Arpino, Laura Mercolini, Roccaldo Sardella, Maurizio Ricci, Enrico Tiacci   +7 more
doaj   +1 more source

Cyclodextrin‐Amino Acid Conjugates: Synthesis and Pharmaceutical Applications

ChemistryEurope, Volume 4, Issue 4, April 2026.
Cyclodextrins (CDs) can be combined with amino acids via host‐guest complexation or by covalent conjugation through various synthetic routes. The chemical modifications introduce structural versatility, multifunctionality, and biocompatibility, which are essential characteristics for designing effective, next‐generation pharmaceutical formulations ...
Andrea Cesari, Nicola Lomuscio, Fabio Bellina   +2 more
wiley   +1 more source

Ferrocene derivatives with planar chirality and their enantioseparation by liquid‐phase techniques

, 2022
International audienceIn the last decade, planar chiral ferrocenes have attracted a growing interest in several fields, particularly in asymmetric catalysis, medicinal chemistry, chiroptical spectroscopy and electrochemistry. In this frame, the access to
Peluso, Paola, Mamane, Victor
core   +1 more source

A Design of Experiments‐Based Chiral HPLC Method for the Quantification of Talazoparib and Enantiomeric Purity Determination in Pharmaceutical Formulations

Chirality, Volume 38, Issue 4, April 2026.
A design of experiments–based chiral HPLC method was developed for the enantiomeric separation and quantification of talazoparib in pharmaceutical formulations. Efficient resolution of the enantiomers (RS > 7) was achieved within 12 min. The method was validated and successfully applied to tablet analysis, and its environmental sustainability was ...
Sakine Atila Karaca, Sona Aliyeva, Duygu Yeniceli   +2 more
wiley   +1 more source

Preparation of Perphenylcarbamoylated B-Cyclodextrin-Silica Hybrid Monolithic Column with Approach for Enantioseparation by Capillary Electrochromatography

, 2012
Preparation of Perphenylcarbamoylated B-Cyclodextrin-Silica Hybrid Monolithic Column with Approach for Enantioseparation by Capillary ...
欧俊杰, 董靖, 邹汉法, 张振宾, 林辉   +4 more
core  

Enantioseparation with liquid membranes

Journal of Chemical Technology & Biotechnology, 2017
AbstractChiral resolution of racemic products is a challenging and important task in the pharmaceutical, agrochemical, flavor, polymer and fragrances industries. One of the options for these challenging separations is to use liquid membranes. Although liquid membranes have been known for almost four decades and have been used for optical resolutions ...
Angelo Gössi, Wolfgang Riedl, Boelo Schuur   +2 more
openaire   +2 more sources

Hexahydroquinoline Featuring Amide Functionality: A Promising Scaffold With Calcium Channel Blocking Activity

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT Hexahydroquinoline (HHQ) is a widely recognized scaffold that has garnered considerable attention owing to its diverse pharmacological properties. The structure of HHQ includes a 1,4‐dihydropyridine (DHP) ring, which serves as the pharmacophore for the predominant class of drugs known as calcium channel blockers.
Ebru Koçak Aslan, Kevin Lam, Sun Huang, Göknil Pelin Coşkun, Ayşe Karagüzel, Katrin Denzinger, Kaan Birgül, Mert Ülgen, Jordan W. Nafie, Onur Şahin, Daniel W. Armstrong, Gerald W. Zamponi, Gerhard Wolber, Miyase Gözde Gündüz   +13 more
wiley   +1 more source