Results 91 to 100 of about 2,821 (224)

Enantioseparation on monolithic molecularly imprinted polymers

, 2006
Among the well known techniques for enantioseparation, lately the MIPs have been proven as an attractive way to obtain pure optically active components.
Seidel-Morgenstern, A., Seebach, A.
core  

Cyclodextrin-Enabled Enantioselective Complexation Study of Cathinone Analogs

Molecules
The characteristic alkaloid component of the leaves of the catnip shrub (Catha edulis) is cathinone, and its synthetic analogs form a major group of recreational drugs. Cathinone derivatives are chiral compounds. In the literature, several chiral methods
András Dohárszky, Eszter Kalydi, Gergely Völgyi, Szabolcs Béni, Ida Fejős   +4 more
doaj   +1 more source

Enantioseparation by crystallization using magnetic substrates

Chemical Science, 2019
Enantiospecific crystallization of the three amino acids asparagine (Asn), glutamic acid hydrochloride (Glu·HCl) and threonine (Thr), induced by ferromagnetic (FM) substrates, is reported.
Francesco Tassinari, Jakob Steidel, Shahar Paltiel, Claudio Fontanesi, Meir Lahav, Yossi Paltiel, Ron Naaman   +6 more
openaire   +4 more sources

Design, Synthesis, Docking Studies and Monoamine Oxidase Inhibition of a Small Library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazoles

Molecules, 2019
New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B.
Paolo Guglielmi, Simone Carradori, Giulio Poli, Daniela Secci, Roberto Cirilli, Giulia Rotondi, Paola Chimenti, Anél Petzer, Jacobus P. Petzer   +8 more
doaj   +1 more source

Chiral Stationary Phases for Liquid Chromatography: Recent Developments

Molecules, 2019
The planning and development of new chiral stationary phases (CSPs) for liquid chromatography (LC) are considered as continuous and evolutionary issues since the introduction of the first CSP in 1938.
Joana Teixeira, Maria Elizabeth Tiritan, Madalena M. M. Pinto, Carla Fernandes   +3 more
doaj   +1 more source

Improvement of electrophoretic enantioseparation of amlodipine by polybrene.

Iranian journal of pharmaceutical research : IJPR, 2012
In chiral and non-chiral electrophoretic resolution of basic drugs, adsorption of analytes to negatively charged capillary wall could lead to poor repeatability of migration time and peak area. In addition, chiral resolutions of basic drugs are commonly performed in low pH buffers.
Zandkarimi, Majid, Shafaati, Alireza, Foroutan, Sayyed Mohsen, Lucy, Charles A.   +3 more
openaire   +2 more sources

Enantioseparation using chromatography and crystallization

, 2010
Due to the improved availability of selective stationary phases and recent developments of more productive operating modes, the number of applications of chiral preparative chromatography has been increased in the last years.
Seidel-Morgenstern, A.
core  

Optimization of the HPLC enantioseparation of 3,3’-dibromo-5,5’-disubstituted-4,4’-bipyridines using immobilized polysaccharide-based chiral stationary phases

, 2013
The HPLC enantioseparation of nine atropisomeric 3,3,5,5-tetrasubstituted-4,4- bipyridines was performed in normal and polar organic (PO) phase modes using two immobilized polysaccharide-based chiral columns, namely, Chiralpak IA and Chiralpak IC. The
Aubert, Emmanuel, Peluso, Paola, COSSU, Sergio Antonio, Paola Peluso, Sergio Cossu, Victor Mamane, Mamane, Victor, Emmanuel Aubert, Cossu, Sergio   +8 more
core   +1 more source

Chiral Recognition Mechanism of Benzyltetrahydroisoquinoline Alkaloids: Cyclodextrin-Mediated Capillary Electrophoresis, Chiral HPLC, and NMR Spectroscopy Study

Molecules
The tetrahydroisoquinoline skeleton is a pharmacologically significant core structure containing chiral centers, making enantiomeric separation crucial due to the potentially distinct biological effects of each enantiomer.
Erzsébet Várnagy, Gergő Tóth, Sándor Hosztafi, Máté Dobó, Ida Fejős, Szabolcs Béni   +5 more
doaj   +1 more source

Monte Carlo simulation of the enantioseparation process

, 2012
By means of Monte Carlo simulation, a study of enantioseparation by capillary electrophoresis has been carried out. A simplified system consisting of two enantiomers S (R) and a selector chiral C, which reacts with the enantiomers to form complexes RC ...
Bustos Giunta, Victor Angel, Acosta, Maria Gimena, Pereyra, Victor Daniel, Gomez, Maria Roxana Anabel   +3 more
core   +1 more source