Results 111 to 120 of about 2,821 (224)

Thermodynamic Study on the Enantioseparation of Benzoin on a Chiralcel OD-RH Column

, 2007
利用Chiralcel OD-H手性柱拆分外消旋安息香化合物制备单一对映体标样,并对其进行圆二色光谱表征。在此基础上,采用甲醇、乙醇、乙腈为流动相考察了安息香在Chiralcel OD-RH柱上的色谱拆分行为和热力学特性。结果表明:以纯甲醇为洗脱液时,(S)-构型先出峰,安息香的拆分过程为焓控;以纯乙醇为洗脱液时,(R)-构型先出峰,拆分过程为熵控;而以纯乙腈为洗脱液时,虽然也是(R)-构型先出峰,但熵和焓对拆分均有贡献。文中还对比了安息香在Chiralcel OD-H柱的拆分性能。This paper
邱进坤, 阮源萍, 成芳
core  

Crystallization of enantiomers : from the phase diagram to crystallization based enantioseparation

Often it is not recognized that crystallization methods can be applied for enantioseparation purposes. Thus, the intention of this lecture is to present and to discuss several aspects relevant to derive the feasibility of crystallization based ...
Lorenz, H.
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Electrochromatographic Enantioseparation of Amino Acids Using Polybutylmethacrylate-based Chiral Monolithic Column by Capillary Electrochromatography

, 2012
This article describes the development of a polybutylmethacrylate-based monolithic capillary column as a chiral stationary phase. The chiral monolithic column was prepared by polymerization of butyl methacrylate (BMA), ethylene dimethacrylate (EDMA), and
DENİZLİ, ADİL, Aydogan, Cemil
core   +1 more source

Enantioseparation performance of CNTs as chiral selectors for the separation of ibuprofen isomers: a dispersion corrected DFT study

, 2017
The enantioseparation of chiral drugs has been of great interest in the modern pharmaceutical industry since the majority of bioorganic compounds are chiral.
Heshmatollah Alinezhad, Mahmood Tajbakhsh, Elham Soleymani, Masoud Darvish Ganji   +3 more
core   +1 more source

[Adrenergic beta-receptor blockers--a group of chiral drugs: enantioseparation in the group of beta-blockers]. [Review] [123 refs] [Slovak]

, 2004
The preparation of pure individual enantiomers represents a topical problem from the standpoint of efficacy and safety of drugs. This paper continues in the preceeding review of the blockers of beta-adrenergic receptors as a group of chiral drugs, which ...
Hutt, A J, Cizmarikova, R, Valentova, J
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β-Cyclodextrin functionalized ionic liquid as high performance liquid chromatography chiral stationary phase for the enantioseparation of natural products and pharmaceuticals / Nurul Yani Rahim [PDF]

, 2017
The demanding for enantiomerically pure (enantiopure) compounds, especially for pharmaceutical field has been attracting great attention during last decades.
Nurul Yani, Rahim
core  

Enzyme assisted physicochemical enantioseparation processes - part I: Production and characterization of recombinant amino acid racemase

, 2009
The demand for enantiopure substances, e.g. for pharmaceutical applications or fine chemical production, continues to increase. This has led to the development of numerous stereoselective synthesis methods.
Wilhelm, S., Würges, K., Wandrey, C., Seidel-Morgenstern, A., Petrusevska, K., Elsner, M., Elsner, M. P., Elsner, M.P., Serci, S., Lütz, S.   +9 more
core   +1 more source

Enantioseparation on monolithic molecularly imprinted polymers

Among the well known techniques for enantioseparation, lately the MIPs have been proven as an attractive way to obtain pure optically active components.
Seidel-Morgenstern, A., Seebach, A.
core  

Enantioseparation using chromatography and crystallization

Due to the improved availability of selective stationary phases and recent developments of more productive operating modes, the number of applications of chiral preparative chromatography has been increased in the last years.
Seidel-Morgenstern, A.
core  

Correction to "An Amino-Acid-Derived Metal-Organic Framework with Large Pores for Unspecific Enantioseparation". [PDF]

J Am Chem Soc
Ma X, Wang M, Li W, Qi J, Tu S, Zhang L, Wang KY, Fu Y, Han Z, Wu X, Zhou HC, Zhu C.   +11 more
europepmc   +1 more source