Results 11 to 20 of about 1,601,441 (195)

Enantiomeric Resolution of Drugs and Metabolites in Polysaccharide- and Protein-Based Chiral Stationary Phases

open access: yesJournal of the Brazilian Chemical Society, 2002
Several chiral stationary phases based on polysaccharide derivatives and proteins were evaluated for the resolution of some chiral drugs and their metabolites.
Bonato Pierina S.   +5 more
doaj   +1 more source

Evaluation and Application of Stationary Phase Selectivity for Drug Analysis [PDF]

open access: yes
Despite the wide range of HPLC stationary phases available for reversed-phase high-performance liquid chromatography (RP-HPLC) and the in-depth studies using probes to highlight differences between them, there is very little in the way of stationary ...
Perera, R. Wimal H.
core   +6 more sources

Application of Natural and Modified Biomacromolecules in Miniaturised Separative Analytical Techniques [PDF]

open access: yes
In pharmaceutical R & D, drug stereochemistry, and consequently the rotation of enantiomers, is very important. Because they act as chiral selectors in vivo, biomacromolecules have been extensively used as chiral selectors for the liquid chromatographic (
Salmon, Andrew B
core   +6 more sources

An Evaluation of Immobilized Poly-(S)-N-(1-phenylethyl)acrylamide Chiral Stationary Phases

open access: yesSeparations, 2022
In this study, brush type and polymer type stationary phases were prepared based on (S)-N-(1-phenylethyl) acrylamide, and the polymeric stationary phase demonstrated superior chiral recognition ability.
Guangying Lu   +4 more
doaj   +1 more source

Retention indices for naturally-occurring chiral and achiral compounds on common gas chromatography chiral stationary phases

open access: yesResults in Chemistry, 2022
Chiral gas chromatography columns were initially developed for enantiomeric separations, however, they are increasingly being used for routine analyses of natural samples which also include many achiral compounds.
David Alavez-Rosas   +2 more
doaj   +1 more source

Mechanistic insights in chiral recognition of μ-opioid receptor agonist tetrapeptide on crown ether chiral stationary phase

open access: yesJournal of Chromatography Open, 2021
Chiral separation of short peptides is of great interest, due to different pharmacological, pharmacokinetic, and/or toxicological activities often possessed by different stereoisomers of chiral drugs.
T. Upmanis, H. Kažoka
doaj   +1 more source

Separation of propranolol enantiomers using chiral HPLC [PDF]

open access: yesKragujevac Journal of Science, 2023
Enantiomers of pharmaceuticals may exhibit different effects because the organism serves as a chiral selector. Enantiomers can now be identified and separated using analytical techniques such as gas chromatography and high-performance liquid ...
Turković Nemanja M.   +3 more
doaj  

Fases estacionárias quirais para cromatografia líquida de alta eficiência Chiral stationary phases for high-performance liquid chromatography

open access: yesQuímica Nova, 2010
The development of Chiral Stationary Phases (CSPs) for high performance liquid chromatography has been studied by various researches around the world, especially, since 1980.
Tiago de Campos Lourenço   +2 more
doaj   +1 more source

Separation Of Methionine Enantiomers By Using Teicoplanin And Cyclofructan Columns

open access: yesNova Biotechnologica et Chimica, 2015
Methionine is a naturally occurring amino acid. Its enantiomeric separation by using high performance liquid chromatography on various types of chiral stationary phases was studied.
Hroboňová Katarína   +5 more
doaj   +1 more source

Enantioselective Liquid Chromatographic Separations Using Macrocyclic Glycopeptide-Based Chiral Selectors

open access: yesMolecules, 2021
Numerous chemical compounds of high practical importance, such as drugs, fertilizers, and food additives are being commercialized as racemic mixtures, although in most cases only one of the isomers possesses the desirable properties. As our understanding
Róbert Berkecz   +3 more
doaj   +1 more source

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