Results 11 to 20 of about 34,318 (205)

Conservation of Chitin-Induced MAPK Signaling Pathways in Rice and Arabidopsis [PDF]

Plant and Cell Physiology, 2017
Perception of microbe-associated molecular patterns (MAMPs) including chitin by pattern recognition receptors (PRRs) rapidly induces activation of mitogen-activated protein kinase (MAPK) cascades. However, how PRRs transmit immune signals to the MAPK cascade is largely unknown.
Kenta, Yamada, Koji, Yamaguchi, Satomi, Yoshimura, Akira, Terauchi, Tsutomu, Kawasaki   +4 more
openaire   +2 more sources

Chitin induces steroid-resistant airway inflammation and airway hyperresponsiveness in mice

Allergology International, 2021
Previous reports have shown that pathogen-associated patterns (PAMPs) induce the production of interleukin (IL)-1β in macrophages. Moreover, studies using mouse models also suggest that chitin, which acts as a PAMP, induces adjuvant effects and eosinophilic infiltration in the lung. Thus, we investigated the effects of inhaled chitin in mouse models.We
Tomohito Takeshige, Norihiro Harada, Sonoko Harada, Ayako Ishimori, Yoko Katsura, Hitoshi Sasano, Yuuki Sandhu, Kei Matsuno, Fumihiko Makino, Jun Ito, Ryo Atsuta, Hisaya Akiba, Kazuhisa Takahashi   +12 more
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Chitin induces accumulation in tissue of innate immune cells associated with allergy [PDF]

Nature, 2007
Allergic and parasitic worm immunity is characterized by infiltration of tissues with interleukin (IL)-4- and IL-13-expressing cells, including T-helper-2 cells, eosinophils and basophils. Tissue macrophages assume a distinct phenotype, designated alternatively activated macrophages.
Tiffany A, Reese, Hong-Erh, Liang, Andrew M, Tager, Andrew D, Luster, Nico, Van Rooijen, David, Voehringer, Richard M, Locksley   +6 more
openaire   +2 more sources

TLR-2 and IL-17A in Chitin-Induced Macrophage Activation and Acute Inflammation [PDF]

The Journal of Immunology, 2008
Abstract Chitin is a ubiquitous polysaccharide in fungi, insects, and parasites. To test the hypothesis that chitin is an important immune modulator, we characterized the ability of chitin fragments to regulate murine macrophage cytokine production in vitro and induce acute inflammation in vivo. In this study, we show that chitin is a
Carla A, Da Silva, Dominik, Hartl, Wei, Liu, Chun G, Lee, Jack A, Elias   +4 more
openaire   +2 more sources

Chitin induces upregulation of B7‐H1 on macrophages and inhibits T‐cell proliferation [PDF]

European Journal of Immunology, 2010
AbstractChitin is a highly abundant glycopolymer, which serves as structural component in fungi, arthropods and crustaceans but is not synthesized by vertebrates. However, vertebrates express chitinases and chitinase‐like proteins, some of which are induced by infection with helminths suggesting that chitinous structures may be targets of the immune ...
Claudia J, Wagner, Silke, Huber, Stefanie, Wirth, David, Voehringer   +3 more
openaire   +2 more sources

Chitin-induced T6SS in Vibrio cholerae is dependent on ChiS activation

Microbiology, 2018
Vibrio cholerae regularly colonizes the chitinous exoskeleton of crustacean shells in the aquatic region. The type 6 secretion system (T6SS) in V. cholerae is an interbacterial killing device. This system is thought to provide a competitive advantage to V. cholerae in a polymicrobial community of the aquatic region under nutrient-poor conditions.
Rhishita, Chourashi, Suman, Das, Debarpan, Dhar, Keinosuke, Okamoto, Asish K, Mukhopadhyay, Nabendu Sekhar, Chatterjee   +5 more
openaire   +2 more sources

Polymeric N-Acetyl-D-Glucosamine (Chitin) Induces Prostaglandin E2 in Dogs.

Journal of Veterinary Medical Science, 1995
The level of prostaglandin E2 (PGE2) in the exudate induced by subcutaneous implantation of a complex formed from non-woven fabric of polyester (NWF) and polymeric N-acetyl-D-glucosamine (chitin) (chitin/NWF) or by implantation of NWF in dogs was measured by radioimmunoassay.
MINAMI, Saburo, OKAMOTO, Yoshiharu, MATSUHASHI, Akira, SASHIWA, Hitoshi, SAIMOTO, Hiroyuki, SHIGEMASA, Yoshihiro, TANIGAWA, Takahiko, SUZUKI, Takao, TANIOKA, Shin-ichiro, TANAKA, Yoshinori   +9 more
openaire   +3 more sources

Polymeric N-Acetyl-D-Glucosamine (Chitin) Induces Histionic Activation in Dogs.

Journal of Veterinary Medical Science, 1993
Analyses on the effects of polymeric N-acetyl-D-glucosamine (chitin), which was obtained from squid pen, on histiogenic activation in dogs were carried out with subcutaneous implants (5 x 5 cm2) of polyester non-woven fabric (NWF) supplemented with chitin (chitin group) and NWF (control group).
OKAMOTO, Yoshiharu, MINAMI, Saburo, MATSUHASHI, Akira, SASHIWA, Hitoshi, SAIMOTO, Hiroyuki, SHIGEMASA, Yoshihiro, TANIGAWA, Takahiko, TANAKA, Yoshinori, TOKURA, Seiichi   +8 more
openaire   +3 more sources

The receptor-like cytoplasmic kinase BSR1 mediates chitin-induced defense signaling in rice cells [PDF]

Bioscience, Biotechnology, and Biochemistry, 2017
Abstract Broad-Spectrum Resistance 1 (BSR1) encodes a rice receptor-like cytoplasmic kinase, and enhances disease resistance when overexpressed. Rice plants overexpressing BSR1 are highly resistant to diverse pathogens, including rice blast fungus.
Yasukazu, Kanda, Naoki, Yokotani, Satoru, Maeda, Yoko, Nishizawa, Takashi, Kamakura, Masaki, Mori   +5 more
openaire   +2 more sources

An OsCEBiP/OsCERK1-OsRacGEF1-OsRac1 Module Is an Essential Early Component of Chitin-Induced Rice Immunity [PDF]

Cell Host & Microbe, 2013
OsCEBiP, a chitin-binding protein, and OsCERK1, a receptor-like kinase, are plasma membrane (PM) proteins that form a receptor complex essential for fungal chitin-driven immune responses in rice. The signaling events immediately following chitin perception are unclear. Investigating the spatiotemporal regulation of the rice small GTPase OsRac1, we find
Akamatsu, Akira, Wong, Hann Lin, Fujiwara, Masayuki, Okuda, Jun, Nishide, Keita, Uno, Kazumi, Imai, Keiko, Umemura, Kenji, Kawasaki, Tsutomu, Kawano, Yoji, Shimamoto, Ko   +10 more
openaire   +2 more sources