Results 31 to 40 of about 34,465 (246)

Chitin induces accumulation in tissue of innate immune cells associated with allergy [PDF]

Nature, 2007
Allergic and parasitic worm immunity is characterized by infiltration of tissues with interleukin (IL)-4- and IL-13-expressing cells, including T-helper-2 cells, eosinophils and basophils. Tissue macrophages assume a distinct phenotype, designated alternatively activated macrophages.
Tiffany A, Reese, Hong-Erh, Liang, Andrew M, Tager, Andrew D, Luster, Nico, Van Rooijen, David, Voehringer, Richard M, Locksley   +6 more
openaire   +2 more sources

TLR-2 and IL-17A in Chitin-Induced Macrophage Activation and Acute Inflammation [PDF]

The Journal of Immunology, 2008
Abstract Chitin is a ubiquitous polysaccharide in fungi, insects, and parasites. To test the hypothesis that chitin is an important immune modulator, we characterized the ability of chitin fragments to regulate murine macrophage cytokine production in vitro and induce acute inflammation in vivo. In this study, we show that chitin is a
Carla A, Da Silva, Dominik, Hartl, Wei, Liu, Chun G, Lee, Jack A, Elias   +4 more
openaire   +2 more sources

Interleukin-33 and thymic stromal lymphopoietin, but not interleukin-25, are crucial for development of airway eosinophilia induced by chitin

Scientific Reports, 2021
Exposure to various antigens derived from house dust mites (HDM) is considered to be a risk factor for development of certain allergic diseases such as atopic asthma, atopic dermatitis, rhinitis and conjunctivitis.
Ken Arae, Masashi Ikutani, Kotaro Horiguchi, Sachiko Yamaguchi, Youji Okada, Hiroki Sugiyama, Keisuke Orimo, Hideaki Morita, Hajime Suto, Ko Okumura, Haruhiko Taguchi, Kenji Matsumoto, Hirohisa Saito, Katsuko Sudo, Susumu Nakae   +14 more
doaj   +1 more source

Chitin induces upregulation of B7‐H1 on macrophages and inhibits T‐cell proliferation [PDF]

European Journal of Immunology, 2010
AbstractChitin is a highly abundant glycopolymer, which serves as structural component in fungi, arthropods and crustaceans but is not synthesized by vertebrates. However, vertebrates express chitinases and chitinase‐like proteins, some of which are induced by infection with helminths suggesting that chitinous structures may be targets of the immune ...
Claudia J, Wagner, Silke, Huber, Stefanie, Wirth, David, Voehringer   +3 more
openaire   +2 more sources

Arabidopsis ubiquitin ligase PUB12 interacts with and negatively regulates Chitin Elicitor Receptor Kinase 1 (CERK1). [PDF]

PLoS ONE, 2017
In Arabidopsis, fungal chitin is recognized as a pathogen-associated molecular pattern (PAMP) by the chitin receptor complex containing the lysin-motif (LysM) receptor-like kinases CERK1 and LYK5.
Koji Yamaguchi, Hirohisa Mezaki, Masayuki Fujiwara, Yuki Hara, Tsutomu Kawasaki   +4 more
doaj   +1 more source

Chitin nanofiber elucidates the elicitor activity of polymeric chitin in plants

Frontiers in Plant Science, 2015
Chitin, an N-acetyl-D-glucosamine polymer, is a component of fungal cell walls and a microbe/pathogen-associated molecular pattern that elicits plant defense responses.
Mayumi eEgusa, Hidenori eMatsui, Hidenori eMatsui, Takeshi eUrakami, Sanami eOkuda, Shinsuke eIfuku, Hirofumi eNakagami, Hironori eKaminaka   +7 more
doaj   +1 more source

Arabidopsis CPK5 Phosphorylates the Chitin Receptor LYK5 to Regulate Plant Innate Immunity

Frontiers in Plant Science, 2020
Chitin, a major component of the fungal cell wall, triggers plant innate immunity in Arabidopsis via a receptor complex including two major lysin motif receptor-like kinases, AtLYK5, and AtCERK1.
Congcong Huang, Yijia Yan, Huilin Zhao, Ying Ye, Yangrong Cao   +4 more
doaj   +1 more source

ATL9, a RING zinc finger protein with E3 ubiquitin ligase activity implicated in chitin- and NADPH oxidase-mediated defense responses. [PDF]

PLoS ONE, 2010
Pathogen associated molecular patterns (PAMPs) are signals detected by plants that activate basal defenses. One of these PAMPs is chitin, a carbohydrate present in the cell walls of fungi and in insect exoskeletons.
Marta Berrocal-Lobo, Sophia Stone, Xin Yang, Jay Antico, Judy Callis, Katrina M Ramonell, Shauna Somerville   +6 more
doaj   +1 more source

Chitin-induced T6SS in Vibrio cholerae is dependent on ChiS activation

Microbiology, 2018
Vibrio cholerae regularly colonizes the chitinous exoskeleton of crustacean shells in the aquatic region. The type 6 secretion system (T6SS) in V. cholerae is an interbacterial killing device. This system is thought to provide a competitive advantage to V. cholerae in a polymicrobial community of the aquatic region under nutrient-poor conditions.
Rhishita, Chourashi, Suman, Das, Debarpan, Dhar, Keinosuke, Okamoto, Asish K, Mukhopadhyay, Nabendu Sekhar, Chatterjee   +5 more
openaire   +2 more sources

Physiological and morphological aspects of Aedes aegypti developing larvae: effects of the chitin synthesis inhibitor novaluron. [PDF]

PLoS ONE, 2012
Population control of the dengue vector mosquito, Aedes aegypti, is difficult due to many reasons, one being the development of resistance to neurotoxic insecticides employed.
Luana C Farnesi, José M Brito, Jutta G Linss, Marcelo Pelajo-Machado, Denise Valle, Gustavo L Rezende   +5 more
doaj   +1 more source