Results 61 to 70 of about 7,040 (158)

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Mycosphaerella graminicola LysM Effector-Mediated Stealth Pathogenesis Subverts Recognition Through Both CERK1 and CEBiP Homologues in Wheat

Molecular Plant-Microbe Interactions, 2014
Fungal cell-wall chitin is a well-recognized pathogen-associated molecular pattern. Recognition of chitin in plants by pattern recognition receptors activates pathogen-triggered immunity (PTI).
Wing-Sham Lee, Jason J. Rudd, Kim E. Hammond-Kosack, Kostya Kanyuka   +3 more
doaj   +1 more source

A Virus‐Inducible E3–RLCK–MADS Module Coordinates Suppression of Plant Immunity and Fertility in Rice

Advanced Science, EarlyView.
ABSTRACT Viruses often hijack host developmental programs to promote infection, but the mechanistic links between reproductive regulation and antiviral immunity remain incompletely understood. Here, we identify a virus‐triggered hierarchical degradation cascade that links antiviral immunity and fertility regulation in rice. We show that the rice grassy
Yuansheng Wu, Fengling Wu, Shiting Huang, Denglu Yang, Xin Lei, Xue Zhang, Na Liu, Peng Gan, Chuan Li, Jie Zhang, Ming Wu, Qingxiao Jia, Shanshan Zhao, Jianguo Wu   +13 more
wiley   +1 more source

Advances in Chitosan Nanoparticles: A Comprehensive Review of Properties, Synthesis, Characterization, Multidisciplinary Applications, and Future Perspectives

Journal of Applied Polymer Science, EarlyView.
This review highlights the synthesis of chitosan nanoparticles from natural sources, the thorough characterization of them, and use of microscopic and spectroscopic methods. It emphasizes that it has some indispensable properties such as being non‐toxic, antimicrobial, and capable of controlled drug release.
Mariam Sohail Mansoor, Nayab Raza, Furqana Bibi, Madiha Mumtaz, Asif Abbas, Farasat Haider, Basit Ali   +6 more
wiley   +1 more source

The Rhizoctonia solani RsLysM and RsRlpA effector proteins contribute to virulence by suppressing chitin-triggered immunity and hypersensitive response [PDF]

, 2018
Abstract Rhizoctonia (in Greek “root-killer”) species and particularly R. solani attacks a broad range of plant species and crops. It belongs to Basidiomycota and is a soil-borne pathogen causing mainly damping-off diseases of seedlings and root rot, although it ...
Dölfors, Fredrik, Holmquist, Louise, Moschou, Panagiotis N., Dixelius, Christina, Tzelepis, Georgios   +4 more
openaire   +1 more source

CERK1 is required for chitin-triggered reactive oxygen species generation in melon and is broadly conserved in cucurbits

Plant Signaling & Behavior
CHITIN ELICITOR RECEPTOR KINASE 1 (CERK1), originally identified in Arabidopsis thaliana, encodes a pattern recognition receptor that perceives the fungal cell wall component called chitin to activate immune responses, including the production of ...
Chun Yu Suen, Hiroki Matsuo, Chujia Jin, Ru Zhang, Akira Mine, Yoshitaka Takano   +5 more
doaj   +1 more source

Molecular effects of resistance elicitors from biological origin and their potential for crop protection [PDF]

, 2014
Plants contain a sophisticated innate immune network to prevent pathogenic microbes from gaining access to nutrients and from colonizing internal structures.
Lea eWiesel, Ingo Hein, Booty, David, David eBooty, David Booty, Gilroy, Eleanor M., Eleanor M. Gilroy, Adrian C. Newton, Ingo eHein, Lea Wiesel, Hein, Ingo; id_orcid, Ian eElliott, Birch, Paul R. J.; id_orcid, Ian Elliott, Wiesel, Lea, Paul R. J. Birch, Elliott, Ian, Newton, Adrian C., Eleanor Marjorie Gilroy   +18 more
core   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

Evasion of chitin-triggered immunity by fungal plant pathogens

, 2017
Plants establish intricate relationships with microorganisms that range from mutualistic to pathogenic. In order to prevent colonization by potentially harmful microbes, plant hosts employ surface-localized receptor molecules that perceive ligands, which are either microbe-derived or result from microbe-mediated plant manipulation.
openaire   +3 more sources