Results 21 to 30 of about 4,781 (194)

Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

Pharmaceutics, 2022
YKL-40 (also named chitinase 3 like-1 protein [CHI3L1]) is a secreted chitinase-like protein which is upregulated in cancers and suggested to have pro-tumorigenic activity.
Astrid Zedlitz Johansen, Marco Carretta, Marie-Louise Thorseth, Shawez Khan, Klaire Yixin Fjæstad, Christian Beltoft Brøchner, Hannes Linder, Christina Ankjærgaard, Marco Donia, Inna Chen, Dorte Lisbet Nielsen, Claus Preibisch Behrens, Daniel Hargbøl Madsen   +12 more
doaj   +1 more source

Enzymatic Synthesis and Characterization of Different Families of Chitooligosaccharides and Their Bioactive Properties

Applied Sciences, 2021
Chitooligosaccharides (COS) are homo- or hetero-oligomers of D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) that can be obtained by chitosan or chitin hydrolysis.
Noa Miguez, Peter Kidibule, Paloma Santos-Moriano, Antonio O. Ballesteros, Maria Fernandez-Lobato, Francisco J. Plou   +5 more
doaj   +1 more source

Green-Chemical Strategies for Production of Tailor-Made Chitooligosaccharides with Enhanced Biological Activities

Molecules, 2023
Chitooligosaccharides (COSs) are b-1,4-linked homo-oligosaccharides of N-acetylglucosamine (GlcNAc) or glucosamine (GlcN), and also include hetero-oligosaccharides composed of GlcNAc and GlcN.
Reeba Thomas, Tamo Fukamizo, Wipa Suginta   +2 more
doaj   +1 more source

Reclamation of Marine Chitinous Materials for Chitosanase Production via Microbial Conversion by Paenibacillus macerans [PDF]

, 2018
[[abstract]]: Chitinous materials from marine byproducts elicit great interest among biotechnologists for their potential biomedical or agricultural applications.
Anh Dzung Nguyen, Chien Thang Doan, San-Lang Wang, Thi Ngoc Tran, Van Bon Nguyen   +4 more
core   +1 more source

Identification and Characterization of Three Chitinases with Potential in Direct Conversion of Crystalline Chitin into N,N′-diacetylchitobiose

Marine Drugs, 2022
Chitooligosaccharides (COSs) have been widely used in agriculture, medicine, cosmetics, and foods, which are commonly prepared from chitin with chitinases.
Xue-Bing Ren, Yan-Ru Dang, Sha-Sha Liu, Ke-Xuan Huang, Qi-Long Qin, Xiu-Lan Chen, Yu-Zhong Zhang, Yan-Jun Wang, Ping-Yi Li   +8 more
doaj   +1 more source

A structural and biochemical model of processive chitin synthesis [PDF]

, 2014
Chitin synthases (CHS) produce chitin, an essential component of the fungal cell wall. The molecular mechanism of processive chitin synthesis is not understood, limiting the discovery of new inhibitors of this enzyme class.
Andrew T. Ferenbach, Atkinson, Barny, Bond, Bowen, Cabib, Charnock, Coutinho, D'Haeze, Daan M.F. van Aalten, Debellé, Drew, Gaughran, Helge C. Dorfmueller, Imai, Kamst, Kamst, Kamst, Karnezis, Kathiravan, Källberg, Manoil, Martínez-Rucobo, Masubuchi, Mavingui, Morgan, Nagahashi, Orlean, Rao, Ruiz-Herrera, Semino, Shaw, Streng, Sudoh, Thompson, Uchida, Vladimir S. Borodkin, Xie, Yabe   +38 more
core   +3 more sources

Guanidinylation of Chitooligosaccharides Involving Internal Cyclization of the Guanidino Group on the Reducing End and Effect of Guanidinylation on Protein Binding Ability

Biomolecules, 2019
In order to synthesize a promising material for developing a novel peptide/protein delivery system, guanidinylation of chitooligosaccharides with 1-amidinopyrazole hydrochloride was investigated herein.
Hironori Izawa, Mizuki Kinai, Shinsuke Ifuku, Minoru Morimoto, Hiroyuki Saimoto   +4 more
doaj   +1 more source

Innovative approach for producing injectable, biodegradable materials using chitooligosaccharides and green chemistry [PDF]

, 2009
Although there are a number of injectable biomaterials currently under development, they present some drawbacks such as being based on synthetic polymers, needing toxic or aggressive synthesis procedures or using raw materials with low availability and/
Boesel, L. F., Reis, R. L., San Román, J.   +2 more
core   +1 more source

Potential Medical Applications of Chitooligosaccharides

Polymers, 2022
Chitooligosaccharides, also known as chitosan oligomers or chitooligomers, are made up of chitosan with a degree of polymerization (DP) that is less than 20 and an average molecular weight (MW) that is lower than 3.9 kDa. COS can be produced through enzymatic conversions using chitinases, physical and chemical applications, or a combination of these ...
openaire   +2 more sources

Influence of Preparation Methods of Chitooligosaccharides on Their Physicochemical Properties and Their Anti-Inflammatory Effects in Mice and in RAW264.7 Macrophages

Marine Drugs, 2018
The methods to obtain chitooligosaccharides are tightly related to the physicochemical properties of the end products. Knowledge of these physicochemical characteristics is crucial to describing the biological functions of chitooligosaccharides ...
Ángela Sánchez, María Mengibar, Margarita Fernández, Susana Alemany, Angeles Heras, Niuris Acosta   +5 more
doaj   +1 more source