Results 21 to 30 of about 1,834 (179)

Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

open access: yesPharmaceutics, 2022
YKL-40 (also named chitinase 3 like-1 protein [CHI3L1]) is a secreted chitinase-like protein which is upregulated in cancers and suggested to have pro-tumorigenic activity.
Astrid Zedlitz Johansen   +12 more
doaj   +1 more source

Enzymatic Synthesis and Characterization of Different Families of Chitooligosaccharides and Their Bioactive Properties

open access: yesApplied Sciences, 2021
Chitooligosaccharides (COS) are homo- or hetero-oligomers of D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) that can be obtained by chitosan or chitin hydrolysis.
Noa Miguez   +5 more
doaj   +1 more source

Anti-Inflammatory Activity of Chitooligosaccharides in Vivo [PDF]

open access: yesMarine Drugs, 2010
All the reports to date on the anti-inflammatory activity of chitooligosaccharides (COS) are mostly based on in vitro methods. In this work, the anti-inflammatory activity of two COS mixtures is characterized in vivo (using balb/c mice), following the carrageenan-induced paw edema method.
Fernandes, João C.   +6 more
openaire   +5 more sources

Green-Chemical Strategies for Production of Tailor-Made Chitooligosaccharides with Enhanced Biological Activities

open access: yesMolecules, 2023
Chitooligosaccharides (COSs) are b-1,4-linked homo-oligosaccharides of N-acetylglucosamine (GlcNAc) or glucosamine (GlcN), and also include hetero-oligosaccharides composed of GlcNAc and GlcN.
Reeba Thomas   +2 more
doaj   +1 more source

Identification and Characterization of Three Chitinases with Potential in Direct Conversion of Crystalline Chitin into N,N′-diacetylchitobiose

open access: yesMarine Drugs, 2022
Chitooligosaccharides (COSs) have been widely used in agriculture, medicine, cosmetics, and foods, which are commonly prepared from chitin with chitinases.
Xue-Bing Ren   +8 more
doaj   +1 more source

Antibacterial Activity of Chitooligosaccharides

open access: yesZeitschrift für Naturforschung C, 2008
The aim of this study was to investigate the antibacterial activity of chitooligosaccharide, prepared by partial acid hydrolysis of chitosan, and of an aminoglycosylated derivative, prepared by reductive alkylation of the chitooligosaccharide, against E. coli and S. aureus.
Luis, Lillo   +4 more
openaire   +2 more sources

Guanidinylation of Chitooligosaccharides Involving Internal Cyclization of the Guanidino Group on the Reducing End and Effect of Guanidinylation on Protein Binding Ability

open access: yesBiomolecules, 2019
In order to synthesize a promising material for developing a novel peptide/protein delivery system, guanidinylation of chitooligosaccharides with 1-amidinopyrazole hydrochloride was investigated herein.
Hironori Izawa   +4 more
doaj   +1 more source

Potential Medical Applications of Chitooligosaccharides

open access: yesPolymers, 2022
Chitooligosaccharides, also known as chitosan oligomers or chitooligomers, are made up of chitosan with a degree of polymerization (DP) that is less than 20 and an average molecular weight (MW) that is lower than 3.9 kDa. COS can be produced through enzymatic conversions using chitinases, physical and chemical applications, or a combination of these ...
openaire   +2 more sources

Research progress on effect of chitooligosaccharides in fish intestinal health

open access: yesSiliao yanjiu, 2023
Chitooligosaccharides are positively charged cationic alkaline oligosaccharides composed of N-acetyl-D-glucosamine with β-(1, 4)-glycosidic linkages, which are small molecule oligosaccharides with a polymerization degree of less than 20%, molecular ...
CHEN Zhi-long   +4 more
doaj  

Antidiabetic Effect and Mechanism of Chitooligosaccharides

open access: yesBiological and Pharmaceutical Bulletin, 2010
The aim of this study was to observe the antidiabetic effect and mechanism of chitooligosaccharides (COS). Type 2 diabetic rats were fed a high-energy diet together with an injection of streptozotocin (STZ). After 8 weeks of COS treatment, the changes in glycometabolism, insulin sensitivity, serum hepatic marker enzyme levels, liver glycogen content ...
Ju, Chuanxia   +6 more
openaire   +3 more sources

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