Results 111 to 120 of about 35,049 (259)

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan   +10 more
wiley   +1 more source

Chitosan: Properties and its pharmaceutical and biomedical aspects

open access: yes, 2011
Chitosan, a natural based nontoxic cationic polysaccharide polymer obtained by alkaline deacetylation of chitin, presents excellent properties such as biodegradability, antibacterial and wound-healing activity and immunological properties.

core  

Computational and molecular characterization of Chitosan derivatives by means of graph-theoretic parameters

open access: yesPartial Differential Equations in Applied Mathematics
Chitin and chitosan are the most significant polysaccharides, having a wide range of uses in biopolymers, the biological sciences, and other domains. Its derivatives, hydrogels, are frequently employed in biomedical settings.
Shahid Zaman   +3 more
doaj   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Preparation, characterization, and potential application of chitosan, chitosan derivatives, and chitosan metal nanoparticles in pharmaceutical drug delivery

open access: yes, 2016
Tarek A Ahmed1,2 Bader M Aljaeid11Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; 2Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar ...
Aljaeid BM, Ahmed TA
core  

A Biomimetic Lubricant Captures Hyaluronic Acid In Situ to Regenerate Cartilage: From Bench to Bedside

open access: yesAdvanced Science, EarlyView.
(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin   +12 more
wiley   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang   +3 more
wiley   +1 more source

THERMOGRAVIMETRIC STUDIES OF CHITOSAN DERIVATIVES

open access: yes, 1992
The thermal stabilities of chitosan derivatives (chito; 2-amino-2-deoxy(1-4)-beta-D-glucopyranan) have been studied by thermogravimetry (TG) between 25 and 550-degrees-C under nitrogen flow.
CARDENAS, G, BERNAL, L, TAGLE, LH
core   +1 more source

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