Results 41 to 50 of about 78,010 (256)

Advances in genetic manipulation of Chlamydia trachomatis

Frontiers in Immunology, 2023
Chlamydia trachomatis, one species of Chlamydia spp., has the greatest impact on human health and is the main cause of bacterial sexually transmitted diseases and preventable blindness among all Chamydia spp. species.
Weiqiang Wan, Danni Li, Dan Li, Jun Jiao
doaj   +1 more source

The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling [PDF]

, 2014
Chlamydia trachomatis, the causative agent of trachoma and sexually transmitted infections, employs a type III secretion (T3S) system to deliver effector proteins into host epithelial cells to establish a replicative vacuole.
Bastidas, Robert J., Carpenter, Victoria K., Chen, Yi-Shan, Plano, Gregory V., Richards, Kristian L., Saka, Hector Alex, Valdivia, Raphael H.   +6 more
core   +3 more sources

Electrochemical sensing strategies for on‐site testing of pathogenic nucleic acids

Electrochemical Science Advances, EarlyView.
Abstract Rapid and reliable on‐site pathogen testing is crucial for diagnosing and managing human health. Nucleic acids (NAs) containing genetic information are valuable target molecules for pathogen testing, and sensitive and rapid detection of NAs using electrochemical approaches has been intensively investigated.
Yusuke Kanno, Shuzo Masui, Yusuke Ota, Ryoichi Saito, Takasi Nisisako   +4 more
wiley   +1 more source

Chlamydia trachomatis and cancer [PDF]

Sexually Transmitted Infections, 2001
Genital Chlamydia trachomatis infections have been recognised as a major public health problem. The World Health Organization (WHO) estimates that 50 million cases of C trachomatis infection occur each year worldwide.1 C trachomatis is the major cause of mucopurulent cervicitis, pelvic inflammatory disease, tubal factor infertility, and ectopic ...
openaire   +3 more sources

Comparison of the efficacy of azithromycin and doxycycline for Chlamydia trachomatis infection in the rectum and urinary tract

Pifu-xingbing zhenliaoxue zazhi
[Objective] The purpose of this study was to compare the efficacy of azithromycin and doxycycline in the treatment of Chlamydia trachomatis infection in the rectum and urinary tract. [Methods] From November 2019 to April 2023, male volunteers who had sex
ZHANG Xiaohui, LIAO Yuying, LIN Xiaoxin, WANG Liuyuan, CHEN Huiru, WU Yujiao, XIE Dongmei, KE Wujian, LI Xiuwen, ZHAO Peizhen, YANG Ligang   +10 more
doaj   +1 more source

ADAR1 mRNA quantification for predicting HSIL in persons with HIV and abnormal anal cytology

International Journal of Cancer, EarlyView.
What's New? This study introduces ADAR1 mRNA quantification as a promising biomarker for improving high‐grade squamous intraepithelial lesion (HSIL) prediction in HIV‐positive individuals with abnormal anal cytology. With 92% specificity, it reduces unnecessary high‐resolution anoscopies (HRA) by 77%, offering a more efficient and targeted screening ...
Melissa Bello‐Perez, Paula Mascarell, Marta Fernández‐González, Jose Alberto García, Ana Gutiérrez‐Ortiz de la Tabla, Christian Ledesma, Alba De la Rica, Antonio Galiana, Leo López, Maria Dolores Ocete, Carme Salvador, Concepción Gimeno, Javier García‐Abellán, Sergio Padilla, Félix Gutiérrez, Mar Masiá   +15 more
wiley   +1 more source

Molecular pathogenesis of Chlamydia trachomatis

Frontiers in Cellular and Infection Microbiology, 2023
Chlamydia trachomatis is a strict intracellular human pathogen. It is the main bacterial cause of sexually transmitted infections and the etiologic agent of trachoma, which is the leading cause of preventable blindness. Despite over 100 years since C. trachomatis was first identified, there is still no vaccine.
Brittany Jury, Charlotte Fleming, Wilhelmina M. Huston, Laurence Don Wai Luu   +3 more
openaire   +3 more sources

Chlamydia Trachomatis Infection and Spontaneous Abortion

Indonesian Journal of Obstetrics and Gynecology, 2021
Objective: To determine the correlation between spontaneous abortion and Chlamydia trachomatis infection. Methods: A cross-sectional study was conducted in women who experienced spontaneous abortion.
Rahayu Basir, Eddy Hartono, Eddy R. Moeljono, St. Nur Asni   +3 more
doaj   +1 more source

Distribution of Chlamydia trachomatis genotypes in infertile patients of Cordoba, Argentina [PDF]

, 2013
To detect and characterize Chlamydia trachomatis (C. trachomatis) genotypes in infertile patients of Córdoba, Argentina; 660 endocervical and urethral swabs and semen samples were collected from infertile patients for detection of C. trachomatis by omp A
Cuffini, Cecilia Gabriela, Estofan, Patricia, Frutos, Maria Celia, Kiguen, Ana Ximena, Molina, Rosa Alejandra, Monetti, Marina Soledad, Paglini, Maria Gabriela, Venezuela, Raul Fernando   +7 more
core   +1 more source

Enhancing Dermatology Training in Sexually Transmitted Infections: Outcomes of an EADV Educational Course

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Sexually transmitted infections (STIs), caused by Neisseria gonorrhoeae, Treponema pallidum and Chlamydia trachomatis, are increasing across Europe, which prompts dermatologists to be more involved in their detection and management.
Andrei Tanasov, Michael Waugh, Carmen Lisboa, Claire Dewsnap, Christopher B. Bunker, Derek Freedman, George‐Sorin Tiplica   +6 more
wiley   +1 more source