Results 31 to 40 of about 27,918 (208)

Penicillin kills chlamydia following the fusion of bacteria with Lysosomes and prevents genital inflammatory lesions in C. muridarum-infected mice [PDF]

open access: yes, 2013
The obligate intracellular bacterium Chlamydia exists as two distinct forms. Elementary bodies (EBs) are infectious and extra-cellular, whereas reticulate bodies (RBs) replicate within a specialized intracellular compartment termed an ‘inclusion ...
Delarbre, C.   +7 more
core   +14 more sources

Regulation of the Mitochondrion-Fatty Acid Axis for the Metabolic Reprogramming of Chlamydia trachomatis during Treatment with β-Lactam Antimicrobials

open access: yesmBio, 2021
Infection with the obligate intracellular bacterium Chlamydia trachomatis is the most common bacterial sexually transmitted disease worldwide. Since no vaccine is available to date, antimicrobial therapy is the only alternative in C.
Kensuke Shima   +16 more
doaj   +1 more source

The persistence of chlamydial inclusions in clinically quiescent trachoma.

open access: closedWest African journal of medicine, 1992
Most of the trachoma patients seen at the Guinness Eye Clinic in Kaduna, Northern Nigeria today are in the healed or quiescent stages of evolution and disease intensity is largely trivial. A significant proportion however, seem to have recrudescence of the active stages, a phenomenon that is usually attributed to reinfection.
Babalola Oe, Bage Sd
openalex   +2 more sources

Host Cell Amplification of Nutritional Stress Contributes To Persistence in Chlamydia trachomatis

open access: yesmBio, 2022
Persistence, a viable but non-replicating growth state, has been implicated in diseases caused by Chlamydia trachomatis. Starvation of distinct nutrients produces a superficially similar persistent state, implying convergence on a common intracellular ...
Nick D. Pokorzynski   +2 more
doaj   +1 more source

Laboratory diagnosis of persistent human chlamydial infection [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2013
Diagnostic assays for persistent chlamydial infection are much needed to conduct high-quality, large-scale studies investigating the persistent state in vivo, its disease associations and the response to therapy. Yet in most studies the distinction between acute and persistent infection is based on the interpretation of the data obtained by the assays ...
Mirja ePuolakkainen, Mirja ePuolakkainen
openaire   +5 more sources

Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection [PDF]

open access: yesPathogens and Disease, 2013
The mechanism by which chlamydiae persist in vivo remains undefined; however, chlamydiae in most animals persist in the gastrointestinal tract (GI) and are transmitted via the fecal-oral route. Oral infection of mice with Chlamydia muridarum was previously shown to establish a long-term persistent infection in the GI tract. In this study, BALB/c, DBA/2,
Laxmi Yeruva   +4 more
openaire   +2 more sources

Analysis of polymorphic membrane protein expression in cultured cells Identifies PmpA and PmpH of Chlamydia psittaci as candidate factors in pathogenesis and immunity to infection [PDF]

open access: yes, 2016
The polymorphic membrane protein (Pmp) paralogous families of Chlamydia trachomatis, Chlamydia pneumoniae and Chlamydia abortus are putative targets for Chlamydia vaccine development. To determine whether this is also the case for Pmp family members of C.
Bavoil, Patrik   +7 more
core   +2 more sources

Chlamydial infection from outside to inside [PDF]

open access: yes, 2019
Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic developmental cycle. Specific interactions with the host cell are crucial for the bacteria's survival and amplification because of the reduced chlamydial genome.
Gitsels, Arlieke   +2 more
core   +2 more sources

Chlamydia trachomatis Plasmid Gene Protein 3 Is Essential for the Establishment of Persistent Infection and Associated Immunopathology

open access: yesmBio, 2020
Chlamydia trachomatis is an obligate intracellular bacterial pathogen that causes blinding trachoma and sexually transmitted disease afflicting hundreds of millions of people globally. A fundamental but poorly understood pathophysiological characteristic
Chunfu Yang   +11 more
doaj   +1 more source

Chlamydiosis of dogs and cats in modern cities [PDF]

open access: yesE3S Web of Conferences, 2021
The aim of the research was to conduct an in-depth analysis of the investigation of chlamydial infections occurred in cats and dogs in Kyiv during the last 10 years.
Nedosekov Vitaliy   +6 more
doaj   +1 more source

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