New insights into a persistent problem — chlamydial infections [PDF]
Journal of Clinical Investigation, 2003 Tissue tropism of clinical ocular and genital Chlamydia trachomatis strains is shown to be linked to the tryptophan synthase genotype. It is suggested that, in the presence of IFN-gamma, which depletes available tryptophan, there exist unique host-parasite interactions that may contribute to persistent chlamydial infection.
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What is the excess risk of infertility in women after genital chlamydia infection? A systematic review of the evidence [PDF]
, 2008 Methods: Twelve databases were searched, limited to peer-reviewed literature published from January 1970 to September 2007. Conference abstracts and reference lists from reviews published since 2000 and from key articles were hand-searched.
Goldberg, D.J. +5 more
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Chlamydia Hijacks ARF GTPases To Coordinate Microtubule Posttranslational Modifications and Golgi Complex Positioning. [PDF]
, 2017 The intracellular bacterium Chlamydia trachomatis develops in a parasitic compartment called the inclusion. Posttranslationally modified microtubules encase the inclusion, controlling the positioning of Golgi complex fragments around the inclusion.
Agata Nawrotek +10 more
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Integrating lncRNAs and mRNAs Expression Profiles in Penicillin-Induced Persistent Chlamydial Infection in HeLa Cells [PDF]
Frontiers in Molecular Biosciences, 2022 Chlamydia trachomatis (C. trachomatis) is a major etiological agent of sexually transmitted infection. Some stressing conditions can result in persistent chlamydial infection, which is thought to be associated with severe complications including ectopic pregnancy and tubal factor infertility.
Xiaobao Huang +7 more
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Penicillin induced persistence in Chlamydia trachomatis: high quality time lapse video analysis of the developmental cycle. [PDF]
PLoS ONE, 2009 BACKGROUND:Chlamydia trachomatis is a major human pathogen with a unique obligate intracellular developmental cycle that takes place inside a modified cytoplasmic structure known as an inclusion.
Rachel J Skilton +6 more
doaj +1 more source
TLR3 Deficiency Leads to a Dysregulation in the Global Gene-Expression Profile in Murine Oviduct Epithelial Cells Infected with Chlamydia muridarum [PDF]
, 2019 OBJECTIVE Describe the implementation and effects of Mobile Acute Care for Elders (MACE) consultation at a Veterans Affairs Medical Center (VAMC). DESIGN Retrospective cohort analysis.
Derbigny, Wilbert A, Kumar, Ramesh
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PLoS Pathogens, 2019 The antibiotic, fosmidomycin (FSM) targets the methylerythritol phosphate (MEP) pathway of isoprenoid synthesis by inhibiting the essential enzyme, 1-deoxy-D-xylulose 5-phosphate reductoisomerase (Dxr) and is lethal to intracellular parasites and ...
Jessica A Slade +4 more
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Host nectin-1 is required for efficient Chlamydia trachomatis serovar E development.
Frontiers in Cellular and Infection Microbiology, 2014 Interaction of Herpes Simplex Virus (HSV) glycoprotein D (gD) with the host cell surface during Chlamydia trachomatis/HSV co-infection stimulates chlamydiae to become persistent.
Jennifer Vanover Hall +9 more
doaj +1 more source
c-Myc plays a key role in IFN-γ-induced persistence of Chlamydia trachomatis
eLife, 2022 Chlamydia trachomatis (Ctr) can persist over extended times within their host cell and thereby establish chronic infections. One of the major inducers of chlamydial persistence is interferon-gamma (IFN-γ) released by immune cells as a mechanism of immune
Nadine Vollmuth +10 more
doaj +1 more source
On the Cayley-persistence algebra [PDF]
arXiv, 2022 In this paper, we introduce a persistent (co)homology theory for Cayley digraph grading. We give the algebraic structures of Cayley-persistence object. Specifically, we consider the module structure of persistent (co)homology and show the decomposition of a finitely generated Cayley-persistence module. Moreover, we introduce the persistence-cup product
arxiv