Results 31 to 40 of about 365,054 (191)

Host nectin-1 is required for efficient Chlamydia trachomatis serovar E development.

Frontiers in Cellular and Infection Microbiology, 2014
Interaction of Herpes Simplex Virus (HSV) glycoprotein D (gD) with the host cell surface during Chlamydia trachomatis/HSV co-infection stimulates chlamydiae to become persistent.
Jennifer Vanover Hall, Jennifer Vanover Hall, Jingru eSun, Jessica eSlade, Jessica eSlade, Jennifer eKintner, Marissa eBambino, Judy eWhittimore, Robert V. Schoborg, Robert V. Schoborg   +9 more
doaj   +1 more source

Characteristic of local antichlamydial immunity in infertile women

Бюллетень сибирской медицины, 2005
Objective: to determine the presence of C. trachomatis in upper genital tract and humoral immunity an laparoscopic examination in 202 patients with different infertility factors. Chlamydial persistence in endometrial and tubal tissues was correlated with
A. I. Novikov, T. V. Klinyshkova
doaj   +1 more source

Penicillin induced persistence in Chlamydia trachomatis: high quality time lapse video analysis of the developmental cycle. [PDF]

PLoS ONE, 2009
BACKGROUND:Chlamydia trachomatis is a major human pathogen with a unique obligate intracellular developmental cycle that takes place inside a modified cytoplasmic structure known as an inclusion.
Rachel J Skilton, Lesley T Cutcliffen, David Barlow, Yibing Wang, Omar Salim, Paul R Lambden, Ian N Clarke   +6 more
doaj   +1 more source

c-Myc plays a key role in IFN-γ-induced persistence of Chlamydia trachomatis

eLife, 2022
Chlamydia trachomatis (Ctr) can persist over extended times within their host cell and thereby establish chronic infections. One of the major inducers of chlamydial persistence is interferon-gamma (IFN-γ) released by immune cells as a mechanism of immune
Nadine Vollmuth, Lisa Schlicker, Yongxia Guo, Pargev Hovhannisyan, Sudha Janaki-Raman, Naziia Kurmasheva, Werner Schmitz, Almut Schulze, Kathrin Stelzner, Karthika Rajeeve, Thomas Rudel   +10 more
doaj   +1 more source

Epidemiological and clinical trends of sexually transmitted infections. Literature review

Репродуктивная эндокринология, 2021
This article presents modern data on epidemiological trends, pathogenesis, and mechanisms of persistence and acquisition of antibiotic resistance of the most common sexually transmitted infections (STIs): chlamydial infection, gonorrhea, trichomoniasis ...
T.M. Tutchenko, O.A. Burka, I.F. Boyarchuk, A.V. Trampolska, V.V. Iavniuk, L.S. Ostroukh   +5 more
doaj   +1 more source

Effect of female sex hormones on the developmental cycle of Chlamydia abortus compared to a penicillin-induced model of persistent infection

BMC Veterinary Research, 2019
Background Chlamydia abortus, an obligate intracellular pathogen with an affinity for placenta, causes reproductive failure. In non-pregnant animals, an initial latent infection is established until the next gestation, when the microorganism is ...
D. Álvarez, M. R. Caro, A. J. Buendía, C. Schnee, N. Ortega, A. Murcia-Belmonte, J. Salinas   +6 more
doaj   +1 more source

A mathematical model of chlamydial infection incorporating movement of chlamydial particles [PDF]

, 2013
We present a spatiotemporal mathematical model of chlamydial infection, host immune response and spatial movement of infectious particles. The re- sulting partial differential equations model both the dynamics of the infection and changes in infection ...
Simpson, D. P., Simpson, Daniel Peter, Farr, Anna Charisse, Sutton, K. J., Mallet, Dann G., Bagher-Oskouei, M., Bagher-Oskouei, Masoumeh, Farr, A. C., Mallet, D. G., Sutton, Kelly-Jean   +9 more
core   +1 more source

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development

, 2023
Introduction. Azelastine hydrochloride, a second-generation histamine H1 receptor (H1R) antagonist, exhibits anti-chlamydial effects against Chlamydia trachomatis (CT) in HeLa cells (genital infection model).Hypothesis/Gap Statement.
Leonard, Cory Ann, Jasmin Kuratli, Schoborg, Robert, Kuratli, Jasmin, Cory Ann Leonard, Borel, Nicole, Nicole Borel, Robert Schoborg, Leonard, Cory Ann; https://orcid.org/, Borel, Nicole; https://orcid.org/   +9 more
core   +1 more source

Productive and Penicillin-Stressed Chlamydia pecorum Infection Induces Nuclear Factor Kappa B Activation and Interleukin-6 Secretion In Vitro

Frontiers in Cellular and Infection Microbiology, 2017
Nuclear factor kappa B (NFκB) is an inflammatory transcription factor that plays an important role in the host immune response to infection. The potential for chlamydiae to activate NFκB has been an area of interest, however most work has focused on ...
Cory A. Leonard, Robert V. Schoborg, Nicole Borel   +2 more
doaj   +1 more source

HHV6-mediated chlamydial persistence differs from other forms of chlamydial persistence and depends on viral entry.

, 2012
(A,B) HHV6-mediated chlamydial persistence differs from that induced by Penicillin G. HeLa cells were co-infected with Chlamydia and HHV6A (A) or HHV6B (B) for different time intervals in the absence (-PenG) or presence of 10 U/ml of Penicillin G (+PenG).
Adrian Mehlitz (31621), Christine Siegl (127421), Birgit Bergmann (127418), Eva Krause (127426), Bhupesh K. Prusty (127406), Linda Böhme (127412), Thomas Rudel (127432)   +6 more
core   +1 more source