Results 31 to 40 of about 7,718,477 (148)

Conjunctival transcriptome in scarring trachoma. [PDF]

, 2010
Trachoma is a poorly understood immunofibrogenic disease process, initiated by Chlamydia trachomatis. Differences in conjunctival gene expression profiles between Ethiopians with trachomatous trichiasis (with [TTI] or without [TT] inflammation) and ...
Saul N. Rajak, Tolbert, Sonda B, David C. W. Mabey, Weiss, Helen A, Burton, Matthew J, Shoo, Alice, Helen A. Weiss, Manjurano, Alphaxard, Habtamu, Esmail, Martin J. Holland, Emerson, Paul M, Bailey, Robin L, Julien Bauer, Holland, Martin J, Alphaxard Manjurano, Matthew J. Burton, Sonda B. Tolbert, Paul M. Emerson, Esmail Habtamu, Alice Shoo, Mabey, David CW, Bauer, Julien, Rajak, Saul N, Robin L. Bailey   +23 more
core   +1 more source

Evaluating the Antibiotic Susceptibility of Chlamydia – New Approaches for in Vitro Assays

Frontiers in Microbiology, 2018
Pigs are the natural hosts of Chlamydia suis, the only Chlamydia species known to spontaneously acquire homotypic resistance conferred by a class C tetracycline resistance gene.
Hanna Marti, Hanna Marti, Nicole Borel, Deborah Dean, Deborah Dean, Deborah Dean, Deborah Dean, Cory A. Leonard   +7 more
doaj   +1 more source

Studies of human immune responses to various antigenic proteins of Chlamydia trachomatis [PDF]

Chlamydiae are gram-negative bacteria which cause diverse diseases of humans and animals. Chlamydia trachomatis, the focus of this work, causes the blinding eye disease trachoma, and reproductive tract infections.
Felton, John Mark
core   +1 more source

Architecture, Dynamics, and Function of the General Stress Response System in B. subtilis [PDF]

, 2012
Cells exhibit diverse and dynamic responses to stress. However, in many cases it remains unclear what the dynamics are, how they are generated, and why they are beneficial to the cell or organism. To investigate these issues we studied the General Stress
Young, Jonathan Wan
core   +1 more source

Chlamydial infection enhances expression of the polymeric immunoglobulin receptor (pIgR) and transcytosis of IgA [PDF]

, 2017
Problem\ud \ud The pIgR mediates transport of IgA into the lumen of mucosal tissues preventing pathogenic infection. Despite this, the expression of pIgR during chlamydial infections of the male and female reproductive tracts remains poorly understood ...
Beagley, Kenneth, Kenneth W. Beagley, Armitage, Charles W., Connor P. O'Meara, O'Meara, Connor, Charles W. Armitage   +5 more
core   +1 more source

Genomewide Transcriptional Responses of Iron-Starved Chlamydia trachomatis Reveal Prioritization of Metabolic Precursor Synthesis over Protein Translation

mSystems, 2018
Iron is essential for growth and development of Chlamydia. Its long-term starvation in cultured mammalian cells leads to production of aberrant noninfectious chlamydial forms, also known as persistence.
Amanda J. Brinkworth, Mark R. Wildung, Rey A. Carabeo   +2 more
doaj   +3 more sources

CtHtrA: The lynchpin of the chlamydial surface and a promising therapeutic target [PDF]

, 2017
Chlamydia trachomatis is the most prevalent sexually transmitted bacterial infection worldwide and the leading cause of preventable blindness. Reports have emerged of treatment failure, suggesting a need to develop new antibiotics to battle Chlamydia ...
Marsh, James W, Huston, Wilhelmina M, Wilhelmina M Huston, Marsh, James W., Tyndall, Joel D.A., Ong, Vanissa A, Lott, William B, Lott, William B., Joel DA Tyndall, Ong, Vanissa A., Timms, Peter, Tyndall, Joel D A, Peter Timms, William B Lott, Huston, Wilhelmina M., Vanissa A Ong, James W Marsh   +16 more
core   +2 more sources

Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow

VIEW, EarlyView.
Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow. Abstract Metagenomic next‐generation sequencing (mNGS) enables unbiased identification of pathogens directly from clinical specimens. Despite its growing application in
Wen Shu, Qiaomei Guo, Han Yang, Huiqin Jiang, Chunyan He, Xueqing Wang, Yuting Fang, Yue Yin, Liwen Zhong, Zhijing Zhao, Jiatao Lou, Lin Wang   +11 more
wiley   +1 more source

Drivers of Host–Pathogen Community Assemblages in European Forests and Urban Green Spaces

Integrative Zoology, EarlyView.
ABSTRACT Despite advances in understanding infectious diseases, the persistence and re‐emergence of wildlife pathogens continue to raise public and veterinary health concerns. This study investigates the relationship between biodiversity and rodent‐borne diseases in Europe, focusing on habitat alterations and their impact on rodent diversity.
Vincent Sluydts, Marie Bouilloud, Maxime Galan, Hussein Alburkat, Anaïs Bordes, Vincent Bourret, Valeria Colombo, Luc DeBruyn, Lara Dutra, Jana Eccard, Jasmin Firozpoor, Romain Gallet, Maciej Grzybek, Heikki Henttonen, Jens Jacob, Andrew McManus, Tarja Sironen, Peter Stuart, Caroline Tatard, Benjamin Roche, Herwig Leirs, Nathalie Charbonnel   +21 more
wiley   +1 more source

Survival and death of intestinal cells infected by Chlamydia trachomatis.

PLoS ONE, 2019
The sexually transmitted pathogen Chlamydia trachomatis (CT) is able to replicate and survive in human intestinal epithelial cells, being the gastro-intestinal tract a suitable site of residence for this microorganism.
Claudio Foschi, Massimo Bortolotti, Giacomo Marziali, Letizia Polito, Antonella Marangoni, Andrea Bolognesi   +5 more
doaj   +1 more source