Results 21 to 30 of about 19,417 (208)
International Journal of Cancer, EarlyView.What's New? Patients with mantle cell lymphoma showing disease progression within 24 months of primary treatment have worse prognosis than patients with later progression. This population‐based study suggests that although early relapse is especially serious, disease progression more than 6 years after treatment still leads to worse survival than the ...
Sara Ekberg +5 more
wiley +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT The widespread use of antineoplastic drugs in cancer treatment has led to significant concerns regarding the potential health risks posed to healthcare professionals involved in the preparation, administration, and handling of these chemical compounds, including genotoxicity.
Thiago Guedes Pinto +6 more
wiley +1 more source
Low Dose Pegylated Interferon Alpha as a First‐Line Treatment for Necrobiotic Xanthogranuloma
JEADV Clinical Practice, EarlyView.ABSTRACT Necrobiotic xanthogranuloma (NXG) is a rare, progressive granulomatous disorder frequently associated with monoclonal gammopathy, particularly monoclonal gammopathy of undetermined significance (MGUS). It typically presents with indurated to ulcerative yellowish plaques or nodules, often with ocular involvement.
Ishana Dixit +2 more
wiley +1 more source
The DiSC assay - A cost-effective guide to treatment for chronic lymphocytic leukemia? [PDF]
, 1999 The differential staining cytotoxicity (DISC) assay involves in vitro drug panel testing against patient tumor cells to identify optimal therapy. This observational study investigated whether DISC assay guided treatment could improve outcome in patients ...
Bosanquet, A.G. +3 more
core +1 more source
B‐Cell Chronic Lymphocytic Leukemia in a Cat
Veterinary Clinical Pathology, EarlyView.ABSTRACT Background An 8.8‐year‐old male neutered Persian cat was presented with a history of recent intermittent mild lethargy, hyporexia, and weight loss. Physical examination revealed pale mucous membranes, an enlarged right mandibular lymph node, and organomegaly suspected to be an enlarged spleen.
James Andre Mori +3 more
wiley +1 more source
Chemical genetics analysis of an aniline mustard anticancer agent reveals complex I of the electron transport chain as a target [PDF]
, 2011 Supplementary information is available at the Journal of Biological Chemistry website.The antitumor agent 11β (CAS 865070-37-7), consisting of a DNA-damaging aniline mustard linked to an androgen receptor (AR) ligand, is known to form covalent DNA ...
Cossarizza +30 more
core +1 more source
Imaging findings and clinical outcome in three cats with possible inflammatory ureteritis
Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.Abstract Three adult cats presented to our institution for evaluation of non‐specific clinical signs and azotaemia. All cats had sonographic evidence of renal pelvic and ureteral dilation, concerning for a ureteral obstruction without a definitive mechanical cause identified. Anti‐inflammatory doses of corticosteroids were administered over an extended
Elisa L. Heacock +3 more
wiley +1 more source
Caspase 8 activation independent of Fas (CD95/APO-1) signaling may mediate killing of B-chronic lymphocytic leukemia cells by cytotoxic drugs or gamma radiation. [PDF]
, 2001 Ligation of the cell-surface Fas molecule by its ligand (Fas-L) or agonistic anti-Fas monoclonal antibodies results in the cleavage and activation of the cysteine protease procaspase 8 followed by the activation of procaspase 3 and by apoptosis.
Folarin, NI +8 more
core
European Journal of Haematology, Volume 116, Issue 2, Page 104-115, February 2026.ABSTRACT Background/Objectives Bruton tyrosine kinase inhibitors (BTKis) have revolutionized treatment for chronic lymphocytic leukemia (CLL), but cardiovascular (CV) toxicities pose significant challenges. Second‐generation BTKis offer improved target specificity, yet CV risks persist.
Stefano Oliva, Stefano Molica
wiley +1 more source