Results 21 to 30 of about 10,072 (202)

A conservative treatment for eosinophilic cystitis

open access: yesIJU Case Reports, Volume 6, Issue 1, Page 8-12, January 2023., 2023
Introduction Eosinophilic cystitis is a rare condition which causes common symptoms and may mimic other conditions. Eosinophilic cystitis has several causes such as hypereosinophilic syndrome, inflammatory diseases, neoplasia, parasites or fungal infection, IgE‐related diseases, Drug Reaction and Eosinophilia and Systemic Symptoms (DRESS) syndrome, or ...
Franco Alchiede Simonato   +6 more
wiley   +1 more source

Long-term management of a cat with nasopharyngeal lymphoma by chlorambucil [PDF]

open access: yesOpen Veterinary Journal, 2021
Background: Lymphoma in the nasal cavity is the most common tumor of cats' upper respiratory tract. However, the effect of single-agent chlorambucil on nasal or nasopharyngeal lymphoma has not been evaluated in cats.
Kaho Takahashi   +7 more
doaj   +1 more source

Dynamic responsiveness of self‐assembling peptide‐based nano‐drug systems

open access: yesInterdisciplinary Medicine, Volume 1, Issue 1, January 2023., 2023
This review discusses dynamically responsive self‐assembling peptide‐based nano‐drug systems, including the stimulation response, strategy of biomimicry, subcellular internalization, and the applications of peptide nano‐drug materials, and concludes with a brief outlook of their challenges and opportunities in clinical translation.
Yuhan Wang   +6 more
wiley   +1 more source

Nasal Lymphoma with Low Mitotic Index in Three Cats Treated with Chlorambucil and Prednisolone

open access: yesVeterinary Sciences, 2022
Lymphoma is the most common tumor of the nasal cavity in cats. Commonly used treatment modalities are radiotherapy and chemotherapy, or both. Typical chemotherapy protocols used in cats with nasal lymphoma are COP (cyclophosphamide, vincristine ...
Karen W. L. Ng   +3 more
doaj   +1 more source

Chlorambucil-Loaded Graphene-Oxide-Based Nano-Vesicles for Cancer Therapy

open access: yesPharmaceutics, 2023
In this study, the authors have designed biocompatible nano-vesicles using graphene oxide (GO) for the release of chlorambucil (CHL) drugs targeting cancerous cells.
Surabhi Kumari   +7 more
doaj   +1 more source

Effect of Statins in the Watch and Wait Phase of Chronic Lymphocytic Leukemia. [PDF]

open access: yesCancer Med
ABSTRACT Background It is an unclear how cholesterol‐lowering statin drugs affect progression of chronic lymphocytic leukemia (CLL). Methods Clinical records of 57 CLL patients were examined to determine how initiating statins in the “watch and wait” phase of management affected disease progression.
Spaner DE.
europepmc   +2 more sources

Real world risk of infusion reactions and effectiveness of front-line obinutuzumab plus chlorambucil compared with other frontline treatments for chronic lymphocytic leukemia

open access: yesBMC Cancer, 2022
Background Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in North America. Previous studies have shown improved progression free survival (PFS) and response rates in unfit patients treated with obinutuzumab compared to other ...
Nicole Bourrier   +11 more
doaj   +1 more source

Case Report: Long-Term Survival of a Dog With Chronic Lymphocytic Leukemia Treated With Chlorambucil, Prednisolone, and Imatinib

open access: yesFrontiers in Veterinary Science, 2022
A 7-year-old castrated male Poodle dog presented with chronic progressive lymphocytosis. Hematologic and peripheral blood smear findings included remarkable lymphocytosis with well-differentiated small lymphocytes. Cytology of bone marrow aspirate showed
Ga-Won Lee   +6 more
doaj   +1 more source

Cytotoxicity of chlorambucil immobilized on magnetic iron oxide nanoparticles Fe3O4

open access: yesMicro & Nano Letters, 2021
Chlorambucil is a nitrogen mustard alkylating agent used for the treatment of various malignant and non‐malignant cancers. The use of the chemotherapeutic is limited by its toxic side effects which precludes the use of optimal doses.
Julia Nowak‐Jary   +2 more
doaj   +1 more source

Discovery of a potent olaparib–chlorambucil hybrid inhibitor of PARP1 for the treatment of cancer

open access: yesFrontiers in Pharmacology, 2023
Introduction: Development of Poly (ADP-ribose) polymerase (PARP) inhibitors has been extensively studied in cancer treatment. Olaparib, the first approved PARP inhibitor, showed potency in the inhibition of both BRCA (breast cancer associated)-mutated ...
Hongyu Qin   +5 more
doaj   +1 more source

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