Results 51 to 60 of about 2,002,516 (344)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

1-Allyl-2-methylpyridinium chloride

open access: yesIUCrData, 2017
The title molecular salt, C9H12N+·Cl−, was obtained by reaction of 2-methylpyridine and allyl chloride. A network of C—H...Cl hydrogen bonds is observed in the crystal structure.
Gino Bentivoglio   +4 more
doaj   +1 more source

Influences of chloride immersion on zeta potential and chloride in concentration of cement-based materials [PDF]

open access: yes, 2015
In this paper, the zeta potential of freshly mixed cement paste and hardened cement pastes, as well as the concentration index, was measured. The influences of chloride concentration in mixing water and slag content on zeta potential of freshly mixed ...
De Schutter, Geert   +2 more
core  

Changes of pore structure and chloride content in cement pastes after pore solution expression [PDF]

open access: yes, 2020
Pore solution expression is a widely accepted approach to extract pore solution of cement-based materials by appllying high pressure. In this study, the variations of pore solution distribution and chloride content in cement pastes before and after pore ...
De Schutter, Geert   +4 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Regression-based machine learning models for nitrate and chloride prediction in surface water in a small agricultural sand plain sub-watershed in southwestern Ontario, Canada

open access: yesFrontiers in Environmental Science
Machine learning (ML) models have proven to be an efficient technique for better understanding and quantification of surface water quality, especially in agricultural watersheds where considerable anthropogenic activities occur.
Ahmed Elsayed   +5 more
doaj   +1 more source

Phosphonium chloride for thermal storage [PDF]

open access: yes, 1972
Development of systems for storage of thermal energy is discussed. Application of phosphonium chloride for heat storage through reversible dissociation is described.
Heimlich, P. F.   +2 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Synthesis and structures of Cu-Cl-M adducts (M=Zn, Sn, Sb)

open access: yesMain Group Metal Chemistry, 2014
The novel bimetallic adducts [(Ph3P)2CuCl]2.ZnCl2 (1), {[(Me3P)CuCl]2.ZnCl2}n (2), [(Me3P)4Cu]+[(Me3P)2Cu(Cl)2ZnCl2]- (3), (Ph3P)2CuCl.SnCl2 (4), (Me3P)3CuSnCl3 (5), [(Ph3P)2CuCl.SbCl3]2 (6) and (Ph3P)3CuCl.SbCl3 (7) have been synthesized from ...
Kociok-Köhn Gabriele   +3 more
doaj   +1 more source

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