Results 61 to 70 of about 1,813,249 (314)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Method and apparatus for convection control of metallic halide vapor density in a metallic halide laser [PDF]

, 1982
An apparatus is disclosed in which a reservoir containing copper chloride is heated so that the copper chloride is maintained in a liquid form. The apparatus includes a means for flowing a buffer gas (which in the exemplary embodiment is neon) over the ...
Pivirotto, T. J.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Regression-based machine learning models for nitrate and chloride prediction in surface water in a small agricultural sand plain sub-watershed in southwestern Ontario, Canada

Frontiers in Environmental Science
Machine learning (ML) models have proven to be an efficient technique for better understanding and quantification of surface water quality, especially in agricultural watersheds where considerable anthropogenic activities occur.
Ahmed Elsayed, Ahmed Elsayed, Jana Levison, Andrew Binns, Marie Larocque, Pradeep Goel   +5 more
doaj   +1 more source

Study on the Removal of Chloride Ions in an Acidic Solution of Zinc Smelting by Green Method

Separations, 2023
In the process of zinc smelting, when the chloride ion concentration exceeds 100 mg/L, it continuously corrodes the electrode plate and affects the stability of the electrodeposition process.
Zhiwen Xiao, Jing Li, Guang Fu, Xinpei Li, Likun Gu, Chaobo Zhang, Te Zhang, Weibo Yin, Dianchuan Liu, Junchang Liu   +9 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Synthesis and structures of Cu-Cl-M adducts (M=Zn, Sn, Sb)

Main Group Metal Chemistry, 2014
The novel bimetallic adducts [(Ph3P)2CuCl]2.ZnCl2 (1), {[(Me3P)CuCl]2.ZnCl2}n (2), [(Me3P)4Cu]+[(Me3P)2Cu(Cl)2ZnCl2]- (3), (Ph3P)2CuCl.SnCl2 (4), (Me3P)3CuSnCl3 (5), [(Ph3P)2CuCl.SbCl3]2 (6) and (Ph3P)3CuCl.SbCl3 (7) have been synthesized from ...
Kociok-Köhn Gabriele, Mahon Mary F., Molloy Kieran C., Sudlow Anna L.   +3 more
doaj   +1 more source

Integrating-sphere coating [PDF]

, 1973
Sodium chloride, used with proper solvent-dispersant combination, forms very durable reflective coatings. Several other inorganic salts, such as barium sulfate, barium carbonate, sodium fluoride, potassium chloride, sodium hexafluorosilicate, and ...
Stuart, J. W.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source