Results 61 to 70 of about 1,187,186 (299)

Chloride-Mediated Alkene Activation Drives Enantioselective Thiourea and Hydrogen Chloride Co-Catalyzed Prins Cyclizations [PDF]

open access: yes, 2022
The mechanism of chiral hydrogen-bond donor (HBD) and hydrogen chloride (HCl) co-catalyzed Prins cyclizations was analyzed through a combination of experimental and computational methods and revealed to involve an unexpected and previously unrecognized ...
Eric, Jacobsen   +5 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Bread Wheat With High Salinity and Sodicity Tolerance

open access: yesFrontiers in Plant Science, 2019
Soil salinity and sodicity are major constraints to global cereal production, but breeding for tolerance has been slow. Narrow gene pools, over-emphasis on the sodium (Na+) exclusion mechanism, little attention to osmotic stress/tissue tolerance ...
Yusuf Genc   +9 more
doaj   +1 more source

The Prognostic Role of Spot Urinary Sodium and Chloride in a Cohort of Hospitalized Advanced Heart Failure Patients: A Pilot Study

open access: yesLife, 2023
Recent studies have demonstrated the prognostic value of spot urinary sodium (UNa+) in acutely decompensated chronic HF (ADCHF) patients. However, data on the prognostic role of UNa+ and spot urinary chloride (UCl−) in patients with advanced HF are ...
Andrew Xanthopoulos   +11 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The influence of curing and aging on chloride transport through ternary blended cement concrete

open access: yesMateriales de Construccion, 2018
The effect of the extension of the curing period and exposure time to a chloride source on the transport of these ions has been studied in concrete with 100% Portland cement (OPC) and with ternary cement composed of 64% OPC, 30% blast furnace slag (BFS ...
F. J. Luna, Á. Fernández, M. C. Alonso
doaj   +1 more source

Corrosion Behavior of Fiber-Reinforced Concrete—A Review

open access: yesFibers, 2022
Corrosion study of conventional reinforcement in concrete has been accorded wider importance in the last few decades based on the losses occurring in monitoring concrete structures.
Ganesh Naidu Gopu, Sofi Androse Joseph
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

An investigation into the relationship between surface concrete resistivity and chloride conductivity test [PDF]

open access: yes, 2014
Includes bibliographical references.The chloride conductivity test (CCT) is a South African-developed Durability Index (DI) test used for the evaluation and quantification of the quality of concrete cover.
Mutale, Lombe
core   +1 more source

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