Results 71 to 80 of about 1,813,249 (314)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Changes in the chloride content of ground water in Pinellas County, Florida between 1947 and 1956 [PDF]

open access: yes, 1958
In December 1956 the U. S. Geological Survey, in cooperation with the Florida Geological Survey and the Board of County Commissioners of Pinellas County, collected waterlevel and chloride content of water in 94 wells in Pinellas County. First sampled
Brown, D. W.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Estimating the Application Rate of Liquid Chloride Products Based on Residual Salt Concentration on Pavement [PDF]

open access: yes, 2018
This technical report summarizes the results of laboratory testing on asphalt and concrete pavement. A known quantity of salt brine was applied as an anti-icer, followed by snow application, traffic simulation, and mechanical snow removal via simulated ...
Akin, Michelle   +2 more
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Influence of cactus mucilage and marine brown algae extract on the compressive strength and durability of concrete

open access: yesMateriales de Construccion, 2016
This paper presents the mechanical performance and durability of concrete with water/cement (w/c) ratios of 0.30 and 0.60 containing cactus mucilage and brown marine seaweed extract solutions (at 0.5° Brix concentrations). Cylindrical specimens (100 mm x
E. F. Hernández   +2 more
doaj   +1 more source

Calcium-Activated Chloride Channel ANO1/TMEM16A: Regulation of Expression and Signaling

open access: yesFrontiers in Physiology, 2020
Anoctamin-1 (ANO1), also known as TMEM16A, is the most studied member of anoctamin family of calcium-activated chloride channels with diverse cellular functions.
Nickolai O. Dulin
doaj   +1 more source

Probabilistic modeling of chloride penetration with respect to concrete heterogeneity and epoxy-coating on the reinforcement [PDF]

open access: yes, 2019
The presented article demonstrates the probabilistic method based modeling of the 2D chloride ingress into reinforced concrete structures with respect to concrete heterogeneity and epoxy-coated steel reinforcement. Spatial change of concrete diffusion is
Konečný, Petr   +2 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

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