Results 61 to 70 of about 901,749 (313)
Advanced Biology, EarlyView.The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li +10 more
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Reactions of Methylenecyclopropanes with Phenylsulfenyl Chloride and Phenylselenyl Chloride. [PDF]
ChemInform, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Min Shi, Le-Ping Liu
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Advanced Biology, EarlyView.A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso +5 more
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Advanced Engineering Materials, EarlyView.Laser surface texturing significantly improves the corrosion resistance and mechanical strength of 3D‐printed iron polylactic acid (Ir‐PLA) for marine applications. Optimal laser parameters reduce corrosion by 80% and enhance tensile strength by 25% and ductility by 15%.
Mohammad Rezayat +6 more
wiley +1 more source
Applied Sciences, 2017 This study aimed to investigate the chloride-binding capacity of alkali-activated fly ash (denoted as FSW) and slag (denoted as SSW) samples and their synthesized Cl-bearing phases, which are capable of binding and immobilizing chloride when seawater is ...
Yubin Jun, Seyoon Yoon, Jae Eun Oh
doaj +1 more source
Inhalation Toxicity of Vinyl Chloride and Vinylidene Chloride [PDF]
Environmental Health Perspectives, 1977 Exposure of mice to 1000 ppm of vinyl chloride (VC), 6 hr/day, 5 days/week, caused some acute deaths with toxic hepatitis and marked tubular necrosis of the renal cortex. Starting the sixth month, mice exposed to 1000, 250, or 50 ppm of VC became lethargic, lost weight quickly, and died.
R. L. Dixon +6 more
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Advanced Engineering Materials, EarlyView.Ag cluster‐modified K0.5Na0.5NbO3 acts as an efficient piezocatalyst for electrochemical N2 reduction, enhanced by built‐in electric fields under mechanical actuation. Comparative studies between static and actuated electrodes reveal improved performance under dynamic conditions.
Benedict Witulski +7 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Bimetallic structures of Inconel 718 and CuCrZr are fabricated using the laser powder directed energy deposition method. The study reveals a strong dependence of interface characteristics such as width and interfusion on processing and heat treatment strategies.
Hamidreza Javidrad, Bahattin Koc
wiley +1 more source
Determination of Chloride and Sulfate in Trona Ores by Ion Chromatography
Yankuang ceshi, 2013 Through the determination of chloride and sulfate, the contents of salt and sodium sulfate in natural trona ore can be obtained. At present analysis methods are inefficient, causing disadvantages, such as having a time-consuming process, easy pollution ...
WANG Mei-ying +4 more
doaj
JAMA: The Journal of the American Medical Association, 1897 Boston, Jan. 13, 1897. To the Editor: —Salt in excess of what occurs in natural food appears to be necessary with the human family as it is with animals. Both a deprivation of it and a large excess of it, especially in the absence of vegetable food, works evil to the body, producing various sorts of disease both in body and in mind.
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