Results 71 to 80 of about 62,077 (307)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Reações sem solventes sob irradiação de micro-ondas: métodos eficientes para síntese de selenol ésteres e carbamatos de 9-fluorenilmetila [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florinaópolis, 2012No presente trabalho, desenvolveram-se novas rotas sintéticas para a síntese de selenol ésteres ...
Godoi, Marcelo de
core
Frontiers in Materials, 2022 In this study, the electrochemical performance of microcapsules (MCs) containing NaNO2 corrosion inhibitors for steel reinforcements was studied in 0.6 M chloride contaminated simulated concrete pore solutions (SCPS) with varying pH for a period of 28 ...
Jacob Ress +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Enantiomerically Enriched Tetrahydropyridine Allyl Chlorides [PDF]
, 2019 Enantiomerically enriched allyl halides are rare due to their configurational lability. Here we report stable piperidine-based allyl chloride enantiomers.
Sedef Karabiyikoglu (6732359) +4 more
core +3 more sources
The Role of Cracks in Chloride-Induced Corrosion of Carbon Steel in Concrete—Review
Corrosion and Materials Degradation, 2022 The majority of works in the field of chloride-indued corrosion of steel in concrete are focused on the cracks formed by the corrosion products. However, the number of studies on the influence of cracks (pre-cracked concrete) on corrosion is limited ...
Amir Poursaee, Brandon Ross
doaj +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Electrochemistry of thorium in LiCl-KCl eutectic melts [PDF]
, 2007 This work presents a study of the electrochemical properties of Th chloride ions dissolved in a molten LiCl-KCl eutectic, in a temperature range of 693-823 K.
J.-P. Glatz +11 more
core +1 more source