Results 51 to 60 of about 136,070 (312)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Materiales de Construccion, 2003 The distance of concrete structures from the sea is an important aspect when studying the deleterious effect of airborne salinity in marine environment zone.
G. R. Meira +3 more
doaj +1 more source
Applied Sciences, 2022 This paper presents an improved procedure for conducting diagnostics tests on corrosion in reinforced concrete structures. This method consists in drilling cylindrical concrete cores with fragments of secondary steel reinforcement (e.g., spacer bars ...
Mariusz Jaśniok, Tomasz Jaśniok
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
PROBABILISTIC ANALYSIS OF DEPTH AND CARBONATION FRONT DEVELOPMENT IN CONCRETE OF MARINE STRUCTURES
Наука и техника, 2018 On the coast of the Russian Far East the climate is monsoon, which is most pro-nounced in the south and northeast waning. Seasonal change of oceanic and continental influence is reflected in the nature of the climate: summer is moderatelywarm and rainy ...
E. E. Shalyi +3 more
doaj +1 more source
Frontiers in Materials, 2022 In this study, the electrochemical performance of microcapsules (MCs) containing NaNO2 corrosion inhibitors for steel reinforcements was studied in 0.6 M chloride contaminated simulated concrete pore solutions (SCPS) with varying pH for a period of 28 ...
Jacob Ress +2 more
doaj +1 more source
Half a century of research on diatoms in athalassic habitats in central Poland [PDF]
, 2015 The authors would like to dedicate this paper to Prof. Marcin Pliński who started the phycological research in these unique habitats of Central Poland.Part of the geology in the Łódź province was formed during the Upper Permian period when rich ...
Nowicka-Krawczyk, Paulina +2 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Role of Cracks in Chloride-Induced Corrosion of Carbon Steel in Concrete—Review
Corrosion and Materials Degradation, 2022 The majority of works in the field of chloride-indued corrosion of steel in concrete are focused on the cracks formed by the corrosion products. However, the number of studies on the influence of cracks (pre-cracked concrete) on corrosion is limited ...
Amir Poursaee, Brandon Ross
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source