Results 61 to 70 of about 62,077 (307)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Dipole-moment-driven diesel soot oxidation in the presence of alkali metal chlorides [PDF]
, 2018 The dipole moments of alkali metal chlorides were found to be responsible for their catalysis of the oxidation of diesel soot, by strengthening the interaction of the catalysts with the surface C-O complexes of soot and rendering the valence electrons of
Chen, Hui, Zhang, Yexin, Zhang, Jian
core
ON THE EFFECTS OF CHLORIDE OF ZINC, AND CHLORIDE OF LEAD, [PDF]
The Lancetn ...
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Protocol for iron-catalyzed cross-electrophile coupling of aryl chlorides with unactivated alkyl chlorides [PDF]
Summary: Organochlorides are a crucial class of electrophiles in organic synthesis. Here, we present a protocol for the cross-electrophile coupling of aryl chlorides with unactivated alkyl chlorides, facilitated by an iron/B2pin2 catalytic system.
Pengjie Xian +4 more
core +1 more source
Enantiomerically enriched tetrahydropyridine allyl chlorides [PDF]
, 2020 Enantiomerically enriched allyl halides are rare due to their configurational lability. Here we report stable piperidine-based allyl chloride enantiomers.
Palacin, Thomas +4 more
core +2 more sources
Materiales de Construccion, 2003 The distance of concrete structures from the sea is an important aspect when studying the deleterious effect of airborne salinity in marine environment zone.
G. R. Meira +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
PROBABILISTIC ANALYSIS OF DEPTH AND CARBONATION FRONT DEVELOPMENT IN CONCRETE OF MARINE STRUCTURES
Наука и техника, 2018 On the coast of the Russian Far East the climate is monsoon, which is most pro-nounced in the south and northeast waning. Seasonal change of oceanic and continental influence is reflected in the nature of the climate: summer is moderatelywarm and rainy ...
E. E. Shalyi +3 more
doaj +1 more source
Applied Sciences, 2022 This paper presents an improved procedure for conducting diagnostics tests on corrosion in reinforced concrete structures. This method consists in drilling cylindrical concrete cores with fragments of secondary steel reinforcement (e.g., spacer bars ...
Mariusz Jaśniok, Tomasz Jaśniok
doaj +1 more source