Management of Mycosis Fungoides With Chlormethine Hydrochloride Gel in Combination With Systemic Therapies: A Case Series [PDF]
Case Reports in Dermatological MedicineBackground Mycosis fungoides (MF) is a subtype of T‐cell lymphoma that is characterised by the infiltration of malignant T cells into the skin. Treatment approaches usually include skin‐directed therapies for early‐stage disease and, additionally, systemic therapies for advanced stages.
Gabor Dobos +6 more
doaj +6 more sources
Adsorption of Chlormethine Anti-Cancer Drug on Pure and Aluminum-Doped Boron Nitride Nanocarriers: A Comparative DFT Study [PDF]
Pharmaceuticals, 2022 The efficacy of pure and aluminum (Al)-doped boron nitride nanocarriers (B12N12 and AlB11N12) in adsorbing Chlormethine (CM), an anti-cancer drug, was comparatively dissected by means of the density functional theory method.
Mahmoud A. A. Ibrahim +8 more
doaj +5 more sources
Multidisciplinary and personalized approach to the management of mycosis fungoides with chlormethine gel: a collection of clinical experiences [PDF]
Drugs in ContextTopical chlormethine (CL) gel formulation was approved by the EMA in 2017 for the treatment of adult patients with mycosis fungoides (MF). To expand the knowledge on the management of patients with MF, this paper provides an overview of clinical practice
Silvia Alberti Violetti +11 more
doaj +4 more sources
Clinical outcomes of chlormethine gel in mycosis fungoides affecting "sensitive" areas: A retrospective case series. [PDF]
J Dtsch Dermatol GesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 11, Page 1447-1450, November 2025.
Tavoletti G +6 more
europepmc +5 more sources
Chlormethine Gel Versus Chlormethine Ointment for Treatment of Patients with Mycosis Fungoides: A Post-Hoc Analysis of Clinical Trial Data. [PDF]
Am J Clin Dermatol, 2022 Chlormethine gel was approved for treatment of mycosis fungoides, the most common cutaneous T-cell lymphoma, on the basis of results from study 201 and study 202. A post-hoc analysis of study 201 found interesting trends regarding improved efficacy of chlormethine gel vs ointment and noted a potential association between dermatitis and clinical ...
Querfeld C +6 more
europepmc +5 more sources
Topical Chlormethine Gel in the Treatment of Lymphomatoid Papulosis: A Case Report and Literature Review. [PDF]
J Clin MedBackground: Lymphomatoid papulosis (LyP) is a primary cutaneous CD30-positive T-cell lymphoproliferative disorder presenting with self-healing erythematous papulonodular lesions that may ulcerate and scar. Treatment varies by lesion extent, location, and severity.
Teoli M +5 more
europepmc +5 more sources
Successful treatment of lymphomatoid papulosis with chlormethine gel
JDDG: Journal der Deutschen Dermatologischen GesellschaftNo abstract available.
Tassilo Dege +4 more
core +5 more sources
Mechanism of action of chlormethine gel in mycosis fungoides [PDF]
Journal of the European Academy of Dermatology and Venereology, 2023 AbstractMycosis fungoides (MF), the most common type of cutaneous T‐cell lymphoma, is characterized by proliferation of malignant skin‐tropic T cells. Progression from early‐stage disease (skin patches and/or plaques) to more advanced stages (cutaneous tumours, erythroderma or extracutaneous involvement) occurs slowly and can be discontinuous ...
E. Guenova +3 more
core +4 more sources
JID Innovations, 2022 Mycosis fungoides (MF) is a type of cutaneous T-cell lymphoma. Chlormethine (CL) is recommended as first-line therapy for MF, with a major purpose to kill tumor cells through DNA alkylation.
Yun-Tsan Chang +5 more
doaj +2 more sources
Chlormethine Hydrochloride is Not Inferior to Tacrolimus in Treating Steroid-Resistant Nephrotic Syndrome [PDF]
Kidney & Blood Pressure Research, 2018 Background/Aims: The present study aimed to explore the equivalence of CHL and tacrolimus (TAC), despite reports regarding the efficacy and safety of TAC in treating SRNS patients.
Yuan Yang +14 more
doaj +3 more sources