Multidisciplinary and personalized approach to the management of mycosis fungoides with chlormethine gel: a collection of clinical experiences [PDF]
Drugs in ContextTopical chlormethine (CL) gel formulation was approved by the EMA in 2017 for the treatment of adult patients with mycosis fungoides (MF). To expand the knowledge on the management of patients with MF, this paper provides an overview of clinical practice
Silvia Alberti Violetti +11 more
doaj +7 more sources
Management of mycosis fungoides-type cutaneous T-cell lymphoma (MF-CTCL): focus on chlormethine gel [PDF]
Cancer Management and Research, 2019 Daphné Denis,1 Nathalie Beneton,1 Kamel Laribi,2 Hervé Maillard1 1Dermatology Department, Centre Hospitalier Le Mans, Le Mans, France; 2Haematology Department, Centre Hospitalier Le Mans, Le Mans, France Abstract: Mycosis fungoides (MF) is ...
Denis D, Beneton N, Laribi K, Maillard H
doaj +6 more sources
Chlormethine Gel for the Treatment of Mycosis Fungoides Cutaneous T-Cell Lymphoma: In Vitro Release and Permeation Testing [PDF]
Dermatology and Therapy, 2022 INTRODUCTION: The DNA-alkylating agent chlormethine (CL, or mechlorethamine) is approved in several countries worldwide as a 0.016% w/w topical CL gel formulation, to treat mycosis fungoides cutaneous T-cell lymphoma, with a positive benefit/risk ratio ...
Pablo L Ortiz-Romero +2 more
exaly +6 more sources
Clinical outcomes of chlormethine gel in mycosis fungoides affecting "sensitive" areas: A retrospective case series. [PDF]
J Dtsch Dermatol GesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 11, Page 1447-1450, November 2025.
Tavoletti G +6 more
europepmc +4 more sources
Successful treatment of lymphomatoid papulosis with chlormethine gel
JDDG - Journal of the German Society of DermatologyJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 22, Issue 6, Page 826-827, June 2024.
Matthias Goebeler +2 more
exaly +4 more sources
Chlormethine Gel in Combination with Other Therapies in the Treatment of Patients with Mycosis Fungoides Cutaneous T Cell Lymphoma: Three Case Reports [PDF]
Advances in Therapy, 2021 Introduction: Chlormethine gel is a skin-directed therapy recommended for patients with early-stage mycosis fungoides (MF) cutaneous T cell lymphoma.
Fani Karagianni +2 more
exaly +4 more sources
EJC Skin CancerBackground: Mycosis fungoides (MF) is the most common form of a rare cutaneous T-cell lymphoma, often present with patches or plaques on the skin and characterized of malignant T cell infiltration.
Silvia Alberti Violetti +6 more
doaj +4 more sources
Chlormethine Gel for Patients with Mycosis Fungoides Cutaneous T Cell Lymphoma: A Review of Efficacy and Safety in Clinical Trial and Real-World Settings [PDF]
Advances in Therapy, 2022 Mycosis fungoides (MF) is a rare disease and is the most common form of cutaneous T cell lymphoma. Topical chlormethine (CL) gel is the first cytotoxic chemotherapy gel that was specifically developed for treatment of MF.
Christiane Querfeld +2 more
exaly +4 more sources
Chlormethine Gel Versus Chlormethine Ointment for Treatment of Patients with Mycosis Fungoides: A Post-Hoc Analysis of Clinical Trial Data [PDF]
American Journal of Clinical Dermatology, 2022 Chlormethine gel was approved for treatment of mycosis fungoides, the most common cutaneous T-cell lymphoma, on the basis of results from study 201 and study 202. A post-hoc analysis of study 201 found interesting trends regarding improved efficacy of chlormethine gel vs ointment and noted a potential association between dermatitis and clinical ...
Joan Guitart, Christiane Querfeld
exaly +5 more sources
Klinische Ergebnisse von Chlormethin‐Gel bei Mycosis fungoides in “sensiblen” Bereichen: Eine retrospektive Fallserie [PDF]
J Dtsch Dermatol GesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 11, Page 1447-1450, November 2025.
Tavoletti G +6 more
europepmc +3 more sources