Results 31 to 40 of about 817 (172)

Degradation of 3‐chlorobenzoate by thermophilic micro‐organisms [PDF]

Letters in Applied Microbiology, 1997
Thermophilic (75 degrees C), anaerobic biodegradation of chlorobenzoates was investigated using different inocula from geothermal and non-geothermal environments. Microbial dehalogenation of 3-chlorobenzoate (0.5 mmol l-1 was achieved by two mixed cultures growing anaerobically at 75 degrees C.
S E, Maloney, T S, Marks, R J, Sharp
openaire   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, Volume 600, Issue 2, Page 251-266, January 2026.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Dampak Pencemaran Lingkungan Akibat Limbah Industri Pengolahan Ikan di Muncar (Studi Kasus Kawasan Industri Pengolahan Ikan di Muncar – Banyuwangi) [PDF]

, 2008
Muncar area is a regional fish producer. There, we can find big and small scale fish processing industries and even home industries. Those industry produce on the average 1,300 ton/day processed fish. Production activities caused environmental pollution,
Setiyono, S. (Setiyono), Yudo, S. (Satmoko)   +1 more
core  

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds

ChemMedChem, Volume 21, Issue 2, January 2026.
Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley   +1 more source

Development of the Esterase PestE for Amide Bond Synthesis Under Aqueous Conditions: Enzyme Cascades for Converting Waste PET into Tamibarotene

Angewandte Chemie, Volume 137, Issue 2, January 10, 2025.
The esterase PestE shows promiscuous activity in catalysing the formation of a wide range of amides under aqueous conditions and can be integrated into enzyme cascades as demonstrated in the conversion of polyethylene terephthalate (PET) degradation product terephthalate into the leukemia drug tamibarotene.
Ellie Goulding, Lucy C. Ward, Faye E. Allan, Drew Dittman, Jesus E. Salcedo‐Sora, Andrew J. Carnell   +5 more
wiley   +2 more sources

Redisain Instalasi Pengolahan Air Limbah (Ipal) Rumah Sakit Umum Daerah (RSUD) Timika, Papua [PDF]

, 2010
Hospital is playing an important role in serving people who need to get health. On the other hand its occurrence causes some problems as well. One of them is the infectious wastewaters which are potential to cause a dangerous effect for human life. A lot
Rahardjo, P. N. (Petrus), Setiyono, S. (Setiyono)   +1 more
core  

Studies on degradation of chlorinated aromatic hydrocarbon by using immobilized cell crude extract of Pseudomonas aeruginosa [PDF]

, 2010
In this work Pseudomonas aeruginosa (NCIM-2074) has been identified as potential organism to decompose chlorobenzene by its crude extract through immobilization technique. P.
Manikandan, R, Prabhu, HJ, Sivashanmugam, P   +2 more
core   +2 more sources

PAK1 inhibitor NVS‐PAK1‐1 preserves dendritic spines in amyloid/tau exposed neurons and 5xFAD mice

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION Synaptic spine loss in Alzheimer's disease (AD) contributes to cognitive decline. p21‐activated kinase 1 (PAK1), a regulator of spine integrity, is aberrantly activated in AD. We investigated whether PAK1 inhibition might preserve dendritic spines in vitro and in vivo.
Tao Yang, Hasi Huhe, Sean‐Paul Williams, Sukhneet Kaur, Yeonglong Albert Ay, Zachary W. Davis‐Gilbert, Gregory A. Cary, Carolyn Paisie, Robert R. Butler III, Jesse Wiley, Ranjita Betarbet, Haian Fu, Duc Duong, Nicholas T. Seyfried, Karina Leal, Gregory W. Carter, Aled Edwards, Allan I. Levey, Jacob L. Capener, David H. Drewry, Mohammad A. Hossain, Hans J. Oh, Alison D. Axtman, Stacey J. Sukoff Rizzo, Frank M. Longo, The Emory‐Sage‐SGC‐Jax TREAT‐AD Center   +25 more
wiley   +1 more source

The genetic construction of two PCB-degrading bacteria [PDF]

, 1998
Thesis (M.S.)--Michigan State University.
Yaroslav, Hrywna
core   +2 more sources

Exploration of Thioxolone Derivatives: Synthesis, Docking Studies, and Biological Evaluation for Antibacterial and Antidiabetic Activities

ChemistrySelect, Volume 10, Issue 38, October 13, 2025.
Thioxolone derivatives are evaluated for antibacterial and anti‐diabetic potential. Compounds T‐11, T‐12, and T‐13 exhibit potent antibacterial activity against E. coli, B. cereus, and S. aureus, with low MIC values. T‐11 and T‐3 show stronger α‐glucosidase inhibition than acarbose, while molecular docking reveals T‐13 as the strongest binder ...
Thohidjhon Khajavali SK, Satya Sree Nannapaneni, Rambabu Gundla, Naresh Kumar Katari   +3 more
wiley   +1 more source