Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li +8 more
wiley +1 more source
Experimental and computational analyses for elucidation of structural, electronic, thermal, and vibrational properties of ethionamide crystal. [PDF]
Bezerra RDS +8 more
europepmc +1 more source
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi +18 more
wiley +1 more source
A universal, high-quality, and high-yield DNA purification method for mycobacteria, including <i>Mycobacterium tuberculosis</i>: large-scale assessment of the chloroform-bead method. [PDF]
Murase Y +9 more
europepmc +1 more source
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang +9 more
wiley +1 more source
Development of a Generic Bio-Interface for Immuno-Biodetection on an Oxide Surface Targeting Pathogen Bacteria. [PDF]
Zwingelstein T, Leblois T, Humblot V.
europepmc +1 more source
Solvent Vapor Conditioning of Polymer-Polymer Organic Solar Cells. [PDF]
Ho MKH, Bai JH, Png RQ.
europepmc +1 more source
In Vivo Wound Healing and Antimicrobial Activities of the Hydroalcoholic Extract and Solvent Fractions of <i>Arisaema schimperianum</i> Schott. (Araceae) Tuber in Mice. [PDF]
Awoke B +5 more
europepmc +1 more source

