Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source
Preparation of Poly-N-Methylpyrrole Coated Platinum Modified Electrode in Chloroform in the Presence of Various Supporting Electrolytes and Its Use for the Catalytic Oxidation of Ascorbic Acid and Hydroquinone [PDF]
The electrochemical preparation of poly-N-methylpyrrole (PMPy) coated platinum electrode in chloroform in the presence of tetrabutylammonium Perchlorate, hexafluorophosphate, hydrogensulphate, Periodate and Iodide as supporting electrolytes was performed.
Jahanbakhsh Raoof +2 more
doaj
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer +7 more
wiley +1 more source
Removing small amounts of organochlorine compounds from aqueous solutions is important for the water treatment and wastewater treatment. Sorption methods with the use of carbon sorbents proved to be very successful in some cases.
Kirsanov M.P., Shishkin V.V.
doaj +1 more source
3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
Chloroform-methanol protein precipitation from microalgae and Pierce BCA assay v1 [PDF]
Yingyu Hu +2 more
openalex +1 more source
DENTA: A Dual Enzymatic Nanoagent for Self‐Activating Tooth Whitening and Biofilm Disruption
The nanoapatite with dual enzymes (DENTA) accumulates in dentinal tubules, reducing hypersensitivity caused by dental nerve exposure and facilitating continuous ROS generation through salivary glucose for effective, long‐term whitening. The dentin structures remain non‐destructive due to the low concentration of ROS, demonstrating excellent cell ...
Junseok Kim +13 more
wiley +1 more source
Analyzing the Effect of Mixed Solvent Ratios on the Performance of P3HT: ICxA -Based Organic Solar Cells. [PDF]
In this investigation, a formulation was developed as a solution and thin films by combining poly (3-hexylthiophene) (P3HT) and fullerene Indene-C60 multi-adducts (ICxA) with varying solvent ratios. The formulations were prepared under ambient conditions.
raghad hadi, Furqan Almyahi
doaj
SELECTION OF EXTRACTIVE AGENTS FOR THE SEPARATION OF CHLOROFORM - METHANOL - TETRAHYDROFURAN MIXTURE
Variants of the extractive distillation of chloroform - methanol - tetrahydrofuran equimolar mixture with industrial separating agents are considered.
V. M. Raeva, D. I. Sukhov
doaj +1 more source
Evaluation of Ethyl Acetate, Chloroform and Toluene Fractions of <i>Thevetia peruviana</i> (Pers.) K. Schum Methanolic Leaf Extract for Uterotonic Activity [PDF]
Jhuma Samanta +2 more
openalex +1 more source

