Results 41 to 50 of about 367,155 (248)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Preparation of Poly-N-Methylpyrrole Coated Platinum Modified Electrode in Chloroform in the Presence of Various Supporting Electrolytes and Its Use for the Catalytic Oxidation of Ascorbic Acid and Hydroquinone [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2002
The electrochemical preparation of poly-N-methylpyrrole (PMPy) coated platinum electrode in chloroform in the presence of tetrabutylammonium Perchlorate, hexafluorophosphate, hydrogensulphate, Periodate and Iodide as supporting electrolytes was performed.
Jahanbakhsh Raoof   +2 more
doaj  

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

EVALUATING AND IMPROVING THE EFFICIENCY OF THE USE OF ACTIVATED CARBONS FOR THE EXTRACTION OF ORGANOCHLORINE COMPOUNDS IN WATER TREATMENT TECHNOLOGY

open access: yesFoods and Raw Materials, 2016
Removing small amounts of organochlorine compounds from aqueous solutions is important for the water treatment and wastewater treatment. Sorption methods with the use of carbon sorbents proved to be very successful in some cases.
Kirsanov M.P., Shishkin V.V.
doaj   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

open access: yesAdvanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram   +5 more
wiley   +1 more source

DENTA: A Dual Enzymatic Nanoagent for Self‐Activating Tooth Whitening and Biofilm Disruption

open access: yesAdvanced Functional Materials, EarlyView.
The nanoapatite with dual enzymes (DENTA) accumulates in dentinal tubules, reducing hypersensitivity caused by dental nerve exposure and facilitating continuous ROS generation through salivary glucose for effective, long‐term whitening. The dentin structures remain non‐destructive due to the low concentration of ROS, demonstrating excellent cell ...
Junseok Kim   +13 more
wiley   +1 more source

Analyzing the Effect of Mixed Solvent Ratios on the Performance of P3HT: ICxA -Based Organic Solar Cells. [PDF]

open access: yesIranian Journal of Materials Science and Engineering
In this investigation, a formulation was developed as a solution and thin films by combining poly (3-hexylthiophene) (P3HT) and fullerene Indene-C60 multi-adducts (ICxA) with varying solvent ratios. The formulations were prepared under ambient conditions.
raghad hadi, Furqan Almyahi
doaj  

SELECTION OF EXTRACTIVE AGENTS FOR THE SEPARATION OF CHLOROFORM - METHANOL - TETRAHYDROFURAN MIXTURE

open access: yesТонкие химические технологии, 2018
Variants of the extractive distillation of chloroform - methanol - tetrahydrofuran equimolar mixture with industrial separating agents are considered.
V. M. Raeva, D. I. Sukhov
doaj   +1 more source

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