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Pediatrics, 1958
CHLOROTHIAZIDE is a new, orally effective diuretic agent chemically related to acetazolamide. Curiously, it is a considerably less potent carbonic anhydrase inhibitor, at least in vitro and, in vivo, its effect has been found additive to that of acetazolamide as it is to the action of the mercurials.
A. H. Kitchin +2 more
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CHLOROTHIAZIDE is a new, orally effective diuretic agent chemically related to acetazolamide. Curiously, it is a considerably less potent carbonic anhydrase inhibitor, at least in vitro and, in vivo, its effect has been found additive to that of acetazolamide as it is to the action of the mercurials.
A. H. Kitchin +2 more
+7 more sources
European Journal of Pharmaceutical Sciences, 2010 Chlorothiazide (CTZ), unlike other thiazide diuretics, can form salts. An injectable formulation containing the sodium salt is available; however neither the physicochemical characteristics of the salt nor its solid state form have been previously ...
Anne Marie Healy +2 more
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CHLOROTHIAZIDE: AN ORAL DIURETIC
Lancet, The, 1958J R Rees, R I Bayliss, Joanf Zilva
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Archives of Dermatology, 1958
In a recent study, Kalz and Scott 1 investigated some of the cutaneous changes during the menstrual cycle. They found that the skin, similarly to other body tissues, took on added water during the premenstrual period. On the basis of this finding, they employed an oral diuretic premenstrually in a series of patients with acne.
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In a recent study, Kalz and Scott 1 investigated some of the cutaneous changes during the menstrual cycle. They found that the skin, similarly to other body tissues, took on added water during the premenstrual period. On the basis of this finding, they employed an oral diuretic premenstrually in a series of patients with acne.
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Chlorothiazid in Diabetes Insipidus
Nature, 1959LARAGH and his co-workers1 have demonstrated that chlorothiazid administered to normal subjects in the midst of a sustained water diuresis provokes a flow of urine of substantially higher concentration for a given rate of total osmolar output than urine formed by water-loaded subjects to whom meralluride is given.
J D, CRAWFORD, G C, KENNEDY
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