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Two revolutionary drugs were introduced into psychiatry in the early 1950s for the treatment of agitated mental patients - reserpine and chlorpromazine. These drugs initiated the modern era of drug treatment for schizophrenia and other psychoses.
Baumeister, Alan A
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Phototoxicity of chlorpromazine
Journal of Medicinal Chemistry, 1979The constitution of chlorpromazine has been studied in the context of its phototoxicity. Electron transfer from the side chain to the aromatic nucleus of the drug contributes to its instability to light. Even without the side chain, however, chlorophenothiazines appear to be very photolabile, so that it is unlikely that nonphototoxic analogues of ...
N J, Bunce, Y, Kumar, L, Ravanal
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Chlorpromazine and Chlorpromazine Combinations in the Treatment of Dysmenorrhea
American Journal of Obstetrics and Gynecology, 1957W D, CHAMBLIN, J D, CORBIT
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The Journal of Pharmacology and Experimental Therapeutics, 1956
W M, BUTLER, N C, MORAN
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W M, BUTLER, N C, MORAN
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The Irish Journal of Medical Science, 1955
W P, O'KEEFFE, J, SHANAHAN, M B, QUANE
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W P, O'KEEFFE, J, SHANAHAN, M B, QUANE
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