Results 81 to 90 of about 28,288 (192)
ABSTRACT The Epidermal Growth Factor Receptor (EGFR) is a key regulator of neurodevelopment, controlling the proliferation, differentiation, and self‐renewal of neural stem and progenitor cells. Dysregulated EGFR signaling has been implicated in schizophrenia, a neurodevelopmental disorder associated with abnormal cortical maturation.
Tommaso Toffanin +17 more
wiley +1 more source
Objective: Effects of chlorpromazine and haloperidol on erythrocyte glucose 6-phosphate dehydrogenase enzyme activity were investigated in invitro conditions. Methods: Glucose 6- phosphate dehydrogenase was purified from human erythrocyte.
Mehmet Emin Büyükokuroğlu +4 more
doaj
ABSTRACT Drug repurposing presents a cost‐effective and time‐efficient strategy to identify new therapeutic applications for existing drugs. Recent advances in artificial intelligence, including machine learning, deep learning, knowledge graphs, and natural language processing, have revolutionized this field by enabling automated discovery of drug ...
Alaba Bukola Ogungbite, Malusi Sibiya
wiley +1 more source
This review systematically elucidates the multifactorial anti‐aging mechanisms of extracellular vesicles (EVs). By bridging fundamental biology with advanced bioengineering, scalable manufacturing, and clinical translation, it establishes a comprehensive framework for developing next‐generation EVs‐based precision nanotherapeutics to combat systemic ...
Xian Huang +6 more
wiley +1 more source
Chlorpromazine induced cataract in a young patient with schizophrenia
There is resurgence of first generation antipsychotics use due to the metabolic side effects associated with the use of second generation antipsychotics. Lenticular and corneal abnormalities were reported earlier with Chlorpromazine.
Divakaran Anjith +5 more
doaj
IntroductionLoss of proteasome function, proteinopathy, and proteotoxicity may cause neurodegeneration across the human lifespan in several forms of brain injury and disease.
Adriana Amrein Almira +9 more
doaj +1 more source
Aims Women may experience unique mental disorders due to hormone shifts. Rates of schizophrenia and bipolar disorder are similar between genders, but onset and symptoms may differ.
Nervana Elbakary +11 more
doaj +1 more source
A Therapeutic Paradox: Intractable Hiccups in Acute Stroke and Vascular Parkinsonism Following Initiation of Carbidopa/Levodopa. [PDF]
Szafran K +4 more
europepmc +1 more source

