Results 81 to 90 of about 36,001 (235)
Frontiers in Pharmacology, 2019 Schizophrenia is a psychiatric disorder that affects more than 21 million people worldwide. It is an incurable disorder and the primary means of managing symptoms is through administration of pharmacological treatments, which consist heavily of ...
Caroline Brandão-Teles +6 more
doaj +1 more source
Priapism after a Singular Dose of Chlorpromazine
, 2011 A case of priapism in a young Nigerian man following a singular dose of chlorpromazine is presented. Complete detumescence was achieved with needle aspiration and adrenaline infiltration. Potency was retained. A review of relevant literature is done. Key
Suleekwe, EA, EA Suleekwe
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Chlorpromazine versus reserpine for schizophrenia [PDF]
, 2016 Background: In the 1940s reserpine, refined from a plant extract that had been used for centuries, began to be used as a treatment for people with mental disorders and was one of the very first antipsychotic drugs.
Adams, Clive E.
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Indian Journal of Psychological Medicine, 2017 A 22-year-old male diagnosed with bipolar affective disorder presented to us with a 3rd episode mania resistant to both olanzapine and haloperidol as well as electroconvulsive therapy.
Tamonud Modak +5 more
doaj +1 more source
Effects of Chlorpromazine on Spinal Reflex [PDF]
, 1959 1. Action of chlorpromazine on the spinal reflex of cat was studied by injecting the drug intravenously or close arterially. 2. It was concluded that the depression of spinal reflex caused by the chlorpromazine is primarily effected by the reduced ...
Kawabata, Gorou, Shibata, Jiro
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Energetic dysregulations in psychotic disorders: Targets for new therapeutics
The FEBS Journal, EarlyView.The present review synthesizes literature documenting aberrant energy production and use, specifically related to mitochondrial and redox dysregulation, in psychotic disorders. Findings from different levels of investigation—genetic, cellular, and in vivo imaging—converge on aberrant energy metabolism as a hallmark of psychotic disorders.
Jacey Anderson +10 more
wiley +1 more source
Comparison of intramuscular haloperidol and other short-acting injectable antipsychotics for management of acute agitation in an adult inpatient psychiatry unit [PDF]
Mental Health ClinicianIntroduction There is no consensus on the optimal antipsychotic for acute agitation. Whereas haloperidol is frequently used and has proven efficacy, second generation antipsychotics show similar efficacy and improved safety and tolerability.
Sarah Gamcsik, PharmD +1 more
doaj +1 more source
Antipsychotics‐Induced Hyposalivation Mediated by Impaired Salivary Ca2+ Signaling
Oral Diseases, EarlyView.ABSTRACT Objectives Antipsychotic‐induced salivary dysfunction such as hyposalivation is a prevalent clinical challenge that severely compromises oral health and quality of life. Although typical and atypical antipsychotics have their therapeutic target in the central nervous system, their direct molecular mechanisms within the salivary glands remain ...
Chaelin Chung +4 more
wiley +1 more source
Chlorpromazine And Graft Survival An Experimental Study
, 1992 Large number of drugs have been used to make the longer length of the flap to survive in experimental animals. In present study, chlorpromazine has been used in experimental rats. In all, thirty albino rats were experimented.
Dr. Tatsat Misra +3 more
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Circular inference in visual cortical hierarchies in schizophrenia
Psychiatry and Clinical Neurosciences, EarlyView.Aim In schizophrenia, disrupted perceptual processes contribute to positive symptoms. However, it remains unclear how top‐down priors and bottom‐up likelihoods are represented across the hierarchy of visual cortices. To identify these processes within cortical hierarchies, the circular inference model offers a framework to account for the biased ...
Shuhei Hara +7 more
wiley +1 more source